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Systemic Lupus Erythematosus

Identification of microRNA-31 as a novel regulator contributing to impaired interleukin-2 production in T cells from patients with systemic lupus erythematosus

  1. Wei Fan1,†,
  2. Dong Liang2,†,*,
  3. Yuanjia Tang1,†,
  4. Bo Qu1,
  5. Huijuan Cui1,
  6. Xiaobing Luo1,
  7. Xinfang Huang1,
  8. Shunle Chen1,
  9. Brandon W. Higgs3,‡,
  10. Bahija Jallal3,‡,
  11. Yihong Yao3,‡,
  12. John B. Harley2,
  13. Nan Shen4,5,*

Article first published online: 27 OCT 2012

DOI: 10.1002/art.34596

Issue

Arthritis & Rheumatism

Arthritis & Rheumatism

Volume 64, Issue 11, pages 3715–3725, November 2012

Additional Information

How to Cite

Fan, W., Liang, D., Tang, Y., Qu, B., Cui, H., Luo, X., Huang, X., Chen, S., Higgs, B. W., Jallal, B., Yao, Y., Harley, J. B. and Shen, N. (2012), Identification of microRNA-31 as a novel regulator contributing to impaired interleukin-2 production in T cells from patients with systemic lupus erythematosus. Arthritis & Rheumatism, 64: 3715–3725. doi: 10.1002/art.34596

Author Information

  1. 1

    Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences and Shanghai Renji Hospital, Shanghai JiaoTong University School of Medicine, and Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

  2. 2

    Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

  3. 3

    MedImmune, Gaithersburg, Maryland

  4. 4

    Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences and Shanghai Renji Hospital, Shanghai JiaoTong University School of Medicine, and Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

  5. 5

    Division of Rheumatology and the Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

  1. †

    Drs. Fan, Liang, and Tang contributed equally to this work.

  2. ‡

    Drs. Higgs, Jallal, and Yao own stock or stock options in AstraZeneca.

*Division of Rheumatology, Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229

  1. †

    Drs. Fan, Liang, and Tang contributed equally to this work.

  2. ‡

    Drs. Higgs, Jallal, and Yao own stock or stock options in AstraZeneca.

Publication History

  1. Issue published online: 27 OCT 2012
  2. Article first published online: 27 OCT 2012
  3. Accepted manuscript online: 26 JUN 2012 09:31AM EST
  4. Manuscript Accepted: 14 JUN 2012
  5. Manuscript Received: 29 JUN 2011

Funded by

  • National Natural Science Foundation of China. Grant Numbers: 30971632, 81025016
  • National High Technology Research and Development Program of China (863 Program). Grant Number: 2007AA02Z123
  • National Basic Research Program of China (973 Program). Grant Number: 2007CB947900
  • Program of the Shanghai Commission of Science and Technology. Grant Numbers: 08JC1414700, 10JC1409300
  • Chinese Ministry of Health Sector Fund. Grant Numbers: 201202008, 201202004

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