• 1
    Taylor PC, Feldmann M. Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis. Nat Rev Rheumatol 2009; 5: 57882.
  • 2
    Mima T, Nishimoto N. Clinical value of blocking IL-6 receptor. Curr Opin Rheumatol 2009; 21: 22430.
  • 3
    Matsumoto I, Staub A, Benoist C, Mathis D. Arthritis provoked by linked T and B recognition of a glycolytic enzyme. Science 1999; 286: 17325.
  • 4
    Schubert D, Maier B, Morawietz L, Krenn V, Kamradt T. Immunization with glucose-6-phosphate isomerase induces T cell-dependent peripheral polyarthritis in genetically unaltered mice. J Immunol 2004; 172: 45039.
  • 5
    Matsumoto I, Zhang H, Yasukochi T, Iwanami K, Tanaka Y, Inoue A, et al. Therapeutic effects of antibodies to tumor necrosis factor-α, interleukin-6 and cytotoxic T-lymphocyte antigen 4 immunoglobulin in mice with glucose-6-phosphate isomerase induced arthritis. Arthritis Res Ther 2008; 10: R66.
  • 6
    Iwanami K, Matsumoto I, Tanaka-Watanabe Y, Inoue A, Mihara M, Ohsugi Y, et al. Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase. Arthritis Rheum 2008; 58: 75463.
  • 7
    Inoue A, Matsumoto I, Tanaka Y, Iwanami K, Kanamori A, Ochiai N, et al. Tumor necrosis factor α-induced adipose-related protein expression in experimental arthritis and in rheumatoid arthritis. Arthritis Res Ther 2009; 11: R118.
  • 8
    Tanaka Y, Matsumoto I, Iwanami K, Inoue A, Umeda N, Tanaka Y, et al. Six-transmembrane epithelial antigen of prostate 4 (STEAP4) is expressed on monocytes/neutrophils, and is regulated by TNF antagonist in patients with rheumatoid arthritis. Clin Exp Rheumatol 2012; 30: 99102.
  • 9
    Wellen KE, Fucho R, Gregor MF, Furuhashi M, Morgan C, Lindstad T, et al. Coordinated regulation of nutrient and inflammatory response by STAMP2 is essential for metabolic homeostasis. Cell 2007; 129: 53748.
  • 10
    Takagi N, Mihara M, Moriya Y, Nishimoto N, Yoshizaki K, Kishimoto T, et al. Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis. Arthritis Rheum 1998; 41: 211721.
  • 11
    Moldes M, Lasnier F, Gauthereau X, Klein C, Pairault J, Feve B, et al. Tumor necrosis factor-α-induced adipose-related protein (TIARP), a cell-surface protein that is highly induced by tumor necrosis factor-α and adipose conversion. J Biol Chem 2001; 276: 3393846.
  • 12
    Fasshauer M, Kralisch M, Klier M, Lossner U, Bluher M, Chambaut-Guerin AM, et al. Interleukin-6 is a positive regulator of tumor necrosis factor α-induced adipose-related protein in 3T3-L1 adipocytes. FEBS Lett 2004; 560: 1537.
  • 13
    Ohgami RS, Campagna DR, McDonald A, Fleming MD. The Steap proteins are metalloreductases. Blood 2006; 108: 138894.
  • 14
    Sparna T, Retey J, Schmich K, Albrecht U, Naumann K, Gretz N, et al. Genome-wide comparison between IL-17 and combined TNF-α/IL-17 induced genes in primary murine hepatocytes. BMC Genomics 2010; 11: 226.
  • 15
    Ramadoss P, Chiappini F, Biban M, Hollenberg AN. Regulation of hepatic six transmembrane epithelial antigen of prostate 4 (STEAP4) expression by STAT3 and CCAAT/enhancer-binding protein α. J Biol Chem 2010; 285: 1645366.
  • 16
    Wang ZH, Zhang W, Gong HP, Guo ZX, Zhao J, Shang YY, et al. Expression of STAMP2 in monocytes associates with cardiovascular alterations. Eur J Clin Invest 2010; 40: 4906.
  • 17
    Waki H, Tontonoz P. STAMPing out inflammation. Cell 2007; 129: 4512.
  • 18
    Plenge RM, Cotsapas C, Davies L, Price AL, de Bakker PI, Maller J, et al. Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet 2007; 39: 147782.
  • 19
    Thomson W, Barton A, Ke X, Eyre S, Hinks A, Bowes J, et al. Rheumatoid arthritis association at 6q23. Nat Genet 2007; 39: 14313.
  • 20
    Matmati M, Jacques P, Maelfait J, Verheugen E, Kool M, Sze M, et al. A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis. Nat Genet 2011; 43: 90812.
  • 21
    Lally F, Smith E, Filer A, Stone MA, Shaw JS, Nash GB, et al. A novel mechanism of neutrophil recruitment in a coculture model of the rheumatoid synovium. Arthritis Rheum 2005; 52: 34609.
  • 22
    Atsumi T, Ishihara K, Kamimura D, Ikushima H, Ohtani T, Hirota S, et al. A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis. J Exp Med 2002; 196: 97990.
  • 23
    Murakami M, Okuyama Y, Ogura H, Asano S, Arima Y, Tsuruoka M, et al. Local microbleeding facilitates IL-6- and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells. J Exp Med 2011; 208: 10314.
  • 24
    Tanaka Y, Matsumoto I, Iwanami K, Inoue A, Minami R, Umeda N, et al. Six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a tumor necrosis factor α-induced protein that regulates IL-6, IL-8, and cell proliferation in synovium from patients with rheumatoid arthritis. Mod Rheumatol 2012; 22: 12836.