SEARCH

SEARCH BY CITATION

REFERENCES

  • 1
    Phillips K, Clauw DJ.Central pain mechanisms in the rheumatic diseases: future directions [review].Arthritis Rheum2013;65:291302.
  • 2
    Schaible HG, Richter F, Ebersberger A, Boettger MK, Vanegas H, Natura G, et al.Joint pain.Exp Brain Res2009;196:15362.
  • 3
    Feldmann M, Maini RN.Anti-TNFα therapy of rheumatoid arthritis: what have we learned?Annu Rev Immunol2001;19:16396.
  • 4
    McInnes IB, Schett G.The pathogenesis of rheumatoid arthritis.N Engl J Med2011;365:220519.
  • 5
    Richter F, Natura G, Loser S, Schmidt K, Viisanen H, Schaible HG.Tumor necrosis factor causes persistent sensitization of joint nociceptors to mechanical stimuli in rats.Arthritis Rheum2010;62:380614.
  • 6
    Inglis JJ, Notley CA, Essex D, Wilson AW, Feldmann M, Anand P, et al.Collagen-induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade.Arthritis Rheum2007;56:401523.
  • 7
    Boettger MK, Hensellek S, Richter F, Gajda M, Stockigt R, Segond von Banchet G, et al.Antinociceptive effects of tumor necrosis factor α neutralization in a rat model of antigen-induced arthritis: evidence of a neuronal target.Arthritis Rheum2008;58:236878.
  • 8
    Hess A, Axmann R, Rech J, Finzel S, Heindl C, Kreitz S, et al.Blockade of TNFα rapidly inhibits pain responses in the central nervous system.Proc Natl Acad Sci U S A2011;108:37316.
  • 9
    McMahon SB, Malcangio M.Current challenges in glia-pain biology.Neuron2009;64:4654.
  • 10
    Milligan ED, Watkins LR.Pathological and protective roles of glia in chronic pain.Nat Rev Neurosci2009;10:2336.
  • 11
    Clark AK, Gentry C, Bradbury EJ, McMahon SC, Malcangio M.Role of spinal microglia in rat models of peripheral nerve injury and inflammation.Eur J Pain2007;11:22330.
  • 12
    Christianson CA, Corr M, Firestein GS, Mobargha A, Yaksh TL, Svensson CI.Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis.Pain2010;151:394403.
  • 13
    Sagar DR, Burston JJ, Hatway GJ, Woodhams SG, Pearson RG, Bennett AJ.The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain.Mol Pain2011;7:88100.
  • 14
    Ledeboer A, Sloane EM, Milligan ED, Frank MG, Mahony JH, Maier SF, et al.Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation.Pain2005;115:7183.
  • 15
    Boyle DL, Jones TL, Hammaker D, Svensson CI, Rosengren S, Albani S, et al.Regulation of peripheral inflammation by spinal p38 MAP kinase in rats.PLoS Med2006;3:e338.
  • 16
    Boettger MK, Weber K, Grossmann D, Gajda M, Bauer R, Bar KJ, et al.Spinal tumor necrosis factor α neutralization reduces peripheral inflammation and hyperalgesia and suppresses autonomic responses in experimental arthritis: a role for spinal tumor necrosis factor α during induction and maintenance of peripheral inflammation.Arthritis Rheum2010;62:130818.
  • 17
    Vasquez E, Bar KJ, Ebersberger A, Klein B, Vanegas H, Schaible HG.Spinal prostaglandins are involved in the development but not the maintenance of inflammation-induced spinal hyperexcitability.J Neurosci2001;21:90018.
  • 18
    Roth A, Mollenhauer J, Wagner A, Fuhrmann R, Straub A, Venbrocks RA, et al.Intra-articular injections of high-molecular-weight hyaluronic acid have biphasic effects on joint inflammation and destruction in rat antigen-induced arthritis.Arthritis Res Ther2005;7:R67786.
  • 19
    Sakurai H, Suzuki S, Kawasaki N, Nakano H, Okazaki T, Chino A, et al.Tumor necrosis factor-α-induced IKK phosphorylation of NF-κB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway.J Biol Chem2003;278:3691623.
  • 20
    Griffiths RJ.Characterisation and pharmacological sensitivity of antigen arthritis induced by methylated bovine serum albumin in the rat.Agents Actions1992;35:8895.
  • 21
    Vazquez E, Kahlenbach J, Segond von Banchet G, Konig C, Schaible HG, Ebersberger A.Spinal interleukin-6 is an amplifier of arthritic pain in the rat.Arthritis Rheum2012;64:223342.
  • 22
    Brenn D, Richter F, Schaible HG.Sensitization of unmyelinated sensory fibers of the joint nerve to mechanical stimuli by interleukin-6 in the rat: an inflammatory mechanism of joint pain.Arthritis Rheum2007;56:3519.
  • 23
    Shavkunov A, Panova N, Prasai A, Veselenak R, Bourne N, Stoilova-McPhie S, et al.Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex.Assay Drug Dev Technol2012;10:14860.
  • 24
    Van Hauwermeiren F, Vandenbroucke RE, Libert C.Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1.Cytokine Growth Factor Rev2011;22:3119.
  • 25
    Straub RH, Pongratz G, Weidler C, Linde HJ, Kirschning CJ, Gluck T, et al.Ablation of the sympathetic nervous system decreases Gram-negative and increases Gram-positive bacterial dissemination: key roles for tumor necrosis factor/phagocytes and interleukin/lymphocytes.J Infectious Diseases2005;192:56072.
  • 26
    Tsujimoto M, Yip YK, Viltek J.Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells.Proc Natl Acad Sci U S A1985;82:762630.
  • 27
    Valle Y, Ledezma-Lozano IY, Torres-Carrillo N, Padilla-Gutierrez JR, Navarro-Hernandez RE, Vazquez-Del Mercado M, et al.Circulating TNFRI and TNFRII levels correlated with the disease activity score (DAS28) in rheumatoid arthritis.Scand J Rheumatol2009;38:33255.
  • 28
    McCoy MK, Tansey MG.TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease.J Neuroinflammation2008;5:45.
  • 29
    Ebersberger A, Grubb BD, Willingale HL, Gardiner NJ, Nebe J, Schaible HG.The intraspinal release of prostaglandin E2 in a model of acute arthritis is accompanied by an up-regulation of cyclo-oxygenase-2 in the spinal cord.Neuroscience1999;93:77581.
  • 30
    Bao L, Zhu Y, Elhassan AM, Wu Q, Xiao B, Zhu J, et al.Adjuvant-induced arthritis: IL-1β, IL-6 and TNF-α are up-regulated in the spinal cord.Neuroreport2001;12:39058.
  • 31
    Lampa J, Westman M, Kadetoff D, Nordenstedt Agreus A, Le Maitre E, Gillis-Haegerstrand C, et al.Peripheral inflammatory disease associated with centrally activated IL-1 system in humans and mice.Proc Natl Acad Sci U S A2012;109:1272833.
  • 32
    Kawasaki Y, Zhang L, Cheng JK, Ji RR.Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1β, interleukin-6, and tumor necrosis factor-α in regulating synaptic and neuronal activity in the superficial spinal cord.J Neurosci2008;28:518994.
  • 33
    Spicarova D, Nerandzic V, Palecek J.Modulation of spinal cord synaptic activity by tumor necrosis factor α in a model of peripheral neuropathy.J Neuroinflammation2011;8:177.
  • 34
    Zhang L, Berta T, Xu ZZ, Liu T, Park JY, Ji RR.TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2.Pain2011;52:41927.
  • 35
    Neugebauer V, Lucke T, Schaible HG.N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists block the hyperexcitability of dorsal horn neurons during development of acute arthritis in rat's knee joint.J Neurophysiol1993;70:136577.
  • 36
    Korn T, Magnus T, Jung S.Autoantigen specific T cells inhibit glutamate uptake in astrocytes by decreasing expression of astrocytic glutamate transporter GLAST: a mechanism mediated by tumor necrosis factor-α.FASEB J2005;19:187880.
  • 37
    Zhang H, Dougherty PM.Acute inhibition of signalling phenotype of spinal GABAergic neurons by tumour necrosis factor-α.J Physiol2011;89:451126.
  • 38
    Zhang H, Nei H, Dougherty PM.A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-α.J Neurosci2010;30:1284455.