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Arthritis & Rheumatism

Cover image for Arthritis & Rheumatism

April 2008

Volume 58, Issue 4

Pages A19–A20, 915–1206

Currently known as: Arthritis & Rheumatology

  1. In this Issue

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      A cost-effectiveness analysis of RA biologics (pages A19–A20)

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23582

  2. Special Articles

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      Inspire before you retire (pages 915–918)

      Neal S. Birnbaum

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23481

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  3. Rheumatoid Arthritis Clinical Studies

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      Biologic drugs for rheumatoid arthritis in the medicare program: A cost-effectiveness analysis (pages 939–946)

      Allan J. Wailoo, Nick Bansback, Alan Brennan, Kaleb Michaud, Richard M. Nixon and Fred Wolfe

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23374

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    3. You have free access to this content
      Results of a two-year followup study of patients with rheumatoid arthritis who received a combination of abatacept and methotrexate (pages 953–963)

      Joel M. Kremer, Harry K. Genant, Larry W. Moreland, Anthony S. Russell, Paul Emery, Carlos Abud-Mendoza, Jacek Szechiński, Tracy Li, Julie Teng, Jean-Claude Becker and René Westhovens

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23397

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      Golimumab in patients with active rheumatoid arthritis despite treatment with methotrexate: A randomized, double-blind, placebo-controlled, dose-ranging study (pages 964–975)

      Jonathan Kay, Eric L. Matteson, Bhaskar Dasgupta, Peter Nash, Patrick Durez, Stephen Hall, Elizabeth C. Hsia, John Han, Carrie Wagner, Zhenhua Xu, Sudha Visvanathan and Mahboob U. Rahman

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23383

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      Increased cortisol relative to adrenocorticotropic hormone predicts improvement during anti–tumor necrosis factor therapy in rheumatoid arthritis (pages 976–984)

      Rainer H. Straub, Georg Pongratz, Maurizio Cutolo, Carla A. Wijbrandts, Dominique Baeten, Martin Fleck, Fabiola Atzeni, Mathias Grunke, Joachim R. Kalden, Jürgen Schölmerich, Hanns-Martin Lorenz, Paul P. Tak and Piercarlo Sarzi-Puttini

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23385

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      The influence of age at symptom onset and length of followup on mortality in patients with recent-onset inflammatory polyarthritis (pages 985–989)

      Sophia M. Naz, Tracey M. Farragher, Diane K. Bunn, Deborah P. M. Symmons and Ian N. Bruce

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23402

  4. Rheumatoid Arthritis Basic Science Studies

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
    1. You have free access to this content
      Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis (pages 990–1000)

      Inés Colmegna, Alejandro Diaz-Borjon, Hiroshi Fujii, Linda Schaefer, Jörg J. Goronzy and Cornelia M. Weyand

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23287

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      Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis (pages 1001–1009)

      Joanna Stanczyk, Deena M. Leslie Pedrioli, Fabia Brentano, Olga Sanchez-Pernaute, Christoph Kolling, Renate E. Gay, Michael Detmar, Steffen Gay and Diego Kyburz

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23386

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      Genetic association of vasoactive intestinal peptide receptor with rheumatoid arthritis: Altered expression and signal in immune cells (pages 1010–1019)

      Mario Delgado, Gema Robledo, Blanca Rueda, Nieves Varela, Francisco O'Valle, Pedro Hernandez-Cortes, Marta Caro, Gisela Orozco, Elena Gonzalez-Rey and Javier Martin

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23482

  5. Ankylosing Spondylitis

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
    1. You have free access to this content
      Association of interleukin-23 receptor variants with ankylosing spondylitis (pages 1020–1025)

      Proton Rahman, Robert D. Inman, Dafna D. Gladman, Jeff P. Reeve, Lynette Peddle and Walter P. Maksymowych

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23389

  6. Experimental Arthritis

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
    1. You have free access to this content
      In vivo delivery of lentiviral vectors expressing vasoactive intestinal peptide complementary DNA as gene therapy for collagen-induced arthritis (pages 1026–1037)

      Mario Delgado, Miguel G. Toscano, Karim Benabdellah, Marien Cobo, Francisco O'Valle, Elena Gonzalez-Rey and Francisco Martı´n

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23283

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  7. Synovium and Tendon Biology

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
    1. You have free access to this content
    2. You have free access to this content
      Modulation of aggrecan and ADAMTS expression in ovine tendinopathy induced by altered strain (pages 1055–1066)

      M. M. Smith, G. Sakurai, S. M. Smith, A. A. Young, J. Melrose, C. M. Stewart, R. C. Appleyard, J. L. Peterson, R. M. Gillies, A. J. Dart, D. H. Sonnabend and C. B. Little

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23388

  8. Cartilage Biology

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      The effect of glycosaminoglycan loss on chondrocyte viability: A study on porcine cartilage explants (pages 1076–1085)

      Shuhei Otsuki, Diana C. Brinson, Lilo Creighton, Mitsuo Kinoshita, Robert L. Sah, Darryl D'Lima and Martin Lotz

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23381

  9. Clinical Image

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      A patient with a tumor of the foot (page 1085)

      H. A. Martens, H. R. Lebbink and M. D. Posthumus

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23384

  10. Osteoarthritis Basic Science Studies

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      Differential expression of vasoactive intestinal peptide and its functional receptors in human osteoarthritic and rheumatoid synovial fibroblasts (pages 1086–1095)

      Yasmina Juarranz, Irene Gutiérrez-Cañas, Begoña Santiago, Mar Carrión, José L. Pablos and Rosa P. Gomariz

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23403

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      A type I collagen defect leads to rapidly progressive osteoarthritis in a mouse model (pages 1096–1106)

      J. M. Blair-Levy, C. E. Watts, N. M. Fiorientino, E. K. Dimitriadis, J. C. Marini and P. E. Lipsky

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23277

  11. Systemic Lupus Erythematosus Basic Science Studies

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      Requirement of toll-like receptor 7 for pristane-induced production of autoantibodies and development of murine lupus nephritis (pages 1107–1115)

      Emina Savarese, Christian Steinberg, Rahul D. Pawar, Wolfgang Reindl, Shizuo Akira, Hans-Joachim Anders and Anne Krug

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23407

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      Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus (pages 1116–1124)

      Saowalak Hunnangkul, Dorothea Nitsch, Benjamin Rhodes, Sapna Chadha, Cheri A. Roberton, Pedro Pessôa-Lopes, Peter J. Norsworthy, Michelle M. A. Fernando, Peter Charles, Charles Mackworth-Young, David A. Isenberg, John C. Whittaker and Timothy J. Vyse

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23400

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      A B cell apotope of Ro 60 in systemic lupus erythematosus (pages 1125–1129)

      Joanne H. Reed, Michael W. Jackson and Tom P. Gordon

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23377

  12. Systemic Lupus Erythematosus Clinical Studies

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
    1. You have free access to this content
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      Sialic acid–binding Ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus (pages 1136–1145)

      Robert Biesen, Cemal Demir, Fidan Barkhudarova, Joachim R. Grün, Marta Steinbrich-Zöllner, Marina Backhaus, Thomas Häupl, Martin Rudwaleit, Gabriela Riemekasten, Andreas Radbruch, Falk Hiepe, Gerd-Rüdiger Burmester and Andreas Grützkau

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23404

  13. Antiphospholipid Syndrome

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      Beta2-glycoprotein I protects thrombin from inhibition by heparin cofactor II: Potentiation of this effect in the presence of anti–β2-glycoprotein I autoantibodies (pages 1146–1155)

      Soheila Rahgozar, Bill Giannakopoulos, Xiaokai Yan, Jiewei Wei, Jian Cheng Qi, Rosalie Gemmell and Steven A. Krilis

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23387

  14. Systemic Sclerosis

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      Pulmonary capillary endothelial metabolic dysfunction: Severity in pulmonary arterial hypertension related to connective tissue disease versus idiopathic pulmonary arterial hypertension (pages 1156–1164)

      David Langleben, Stylianos E. Orfanos, Michele Giovinazzo, Andrew Hirsch, Murray Baron, Jean-Luc Senécal, Apostolos Armaganidis and John D. Catravas

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23405

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      T cell polarization identifies distinct clinical phenotypes in scleroderma lung disease (pages 1165–1174)

      Francesco Boin, Umberto De Fanis, Susan J. Bartlett, Fredrick M. Wigley, Antony Rosen and Vincenzo Casolaro

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23406

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      Fibroblast-specific perturbation of transforming growth factor β signaling provides insight into potential pathogenic mechanisms of scleroderma-associated lung fibrosis: Exaggerated response to alveolar epithelial injury in a novel mouse model (pages 1175–1188)

      Rachel K. Hoyles, Korsa Khan, Xu Shiwen, Sarah L. Howat, Gisela E. Lindahl, Patricia Leoni, Roland M. du Bois, Athol U. Wells, Carol M. Black, David J. Abraham and Christopher P. Denton

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23379

  15. Childhood Arthritis

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
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      High prevalence of temporomandibular joint arthritis at disease onset in children with juvenile idiopathic arthritis, as detected by magnetic resonance imaging but not by ultrasound (pages 1189–1196)

      Pamela F. Weiss, Bita Arabshahi, Ann Johnson, Larissa T. Bilaniuk, Deborah Zarnow, Anne Marie Cahill, Chris Feudtner and Randy Q. Cron

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23401

  16. Vasculitis

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
    1. You have free access to this content
  17. Letters

    1. Top of page
    2. In this Issue
    3. Special Articles
    4. Rheumatoid Arthritis Clinical Studies
    5. Rheumatoid Arthritis Basic Science Studies
    6. Ankylosing Spondylitis
    7. Experimental Arthritis
    8. Synovium and Tendon Biology
    9. Cartilage Biology
    10. Clinical Image
    11. Osteoarthritis Basic Science Studies
    12. Systemic Lupus Erythematosus Basic Science Studies
    13. Systemic Lupus Erythematosus Clinical Studies
    14. Antiphospholipid Syndrome
    15. Systemic Sclerosis
    16. Childhood Arthritis
    17. Vasculitis
    18. Letters
    1. You have free access to this content
      Performing trials in children with rheumatic diseases: Comment on the editorial by Lehman (pages 1201–1202)

      Nicolino Ruperto, Alberto Martini, Daniel J. Lovell and Edward H. Giannini

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23413

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      Clinical trials in pediatric rheumatology: Comment on the editorial by Lehman (pages 1202–1203)

      Esi Morgan DeWitt, Stacy Payne Ardoin, C. Egla Rabinovich and Laura E. Schanberg

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23411

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      Reply (page 1203)

      Thomas J. A. Lehman

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23412

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      Reply (page 1204)

      Craig M. Flory

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23483

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      Reply (page 1205)

      Judith A. M. Wessels, Sjoerd M. van der Kooij, Tom W. J. Huizinga and Henk-Jan Guchelaar

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23484

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      Reply (page 1206)

      Johannes von Kempis and Wilke Beuthien

      Article first published online: 27 MAR 2008 | DOI: 10.1002/art.23409

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