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Arthritis & Rheumatism

Cover image for Vol. 64 Issue 6

June 2012

Volume 64, Issue 6

Pages 1697–2054

Currently known as: Arthritis & Rheumatology

  1. In This Issue

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      In this issue

      Version of Record online: 29 MAY 2012 | DOI: 10.1002/art.34531

  2. Review

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Osteoarthritis: A disease of the joint as an organ (pages 1697–1707)

      Richard F. Loeser, Steven R. Goldring, Carla R. Scanzello and Mary B. Goldring

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34453

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  3. Editorial

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
  4. Unresolved Questions in Rheumatology

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
  5. Rheumatoid Arthritis

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients (pages 1720–1729)

      Hani S. El-Gabalawy, David B. Robinson, Irene Smolik, Donna Hart, Brenda Elias, Keng Wong, Christine A. Peschken, Carol A. Hitchon, Xuan Li, Charles N. Bernstein, Marianna M. Newkirk and Marvin J. Fritzler

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34449

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      A phase II, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of MDX-1100, a fully human anti-CXCL10 monoclonal antibody, in combination with methotrexate in patients with rheumatoid arthritis (pages 1730–1739)

      Michael Yellin, Igor Paliienko, Andra Balanescu, Semen Ter-Vartanian, Vira Tseluyko, Li-An Xu, Xiaolu Tao, Pina M. Cardarelli, Heidi LeBlanc, Geoff Nichol, Codrina Ancuta, Rodica Chirieac and Allison Luo

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34330

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      Association of anticytomegalovirus seropositivity with more severe joint destruction and more frequent joint surgery in rheumatoid arthritis (pages 1740–1749)

      Matthias Pierer, Kathrin Rothe, Dagmar Quandt, Anett Schulz, Manuela Rossol, Roger Scholz, Christoph Baerwald and Ulf Wagner

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34346

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      Brief Report: A phase IIa, randomized, double-blind, placebo-controlled trial of apilimod mesylate, an interleukin-12/interleukin-23 inhibitor, in patients with rheumatoid arthritis (pages 1750–1755)

      Sarah Krausz, Maria J. H. Boumans, Danielle M. Gerlag, Joelle Lufkin, Arno W. R. van Kuijk, Alian Bakker, Maarten de Boer, Beatrijs M. Lodde, Kris A. Reedquist, Eric W. Jacobson, Michael O'Meara and Paul P. Tak

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34339

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      Brief Report: Airways abnormalities and rheumatoid arthritis–related autoantibodies in subjects without arthritis: Early injury or initiating site of autoimmunity? (pages 1756–1761)

      M. Kristen Demoruelle, Michael H. Weisman, Philip L. Simonian, David A. Lynch, Peter B. Sachs, Isabel F. Pedraza, Annie R. Harrington, Jason R. Kolfenbach, Christopher C. Striebich, Quyen N. Pham, Colin D. Strickland, Brian D. Petersen, Mark C. Parish, Lezlie A. Derber, Jill M. Norris, V. Michael Holers and Kevin D. Deane

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34344

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      T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4ig but is successfully treated by interleukin-17 neutralization (pages 1762–1770)

      Marije I. Koenders, Renoud J. Marijnissen, Leo A. B. Joosten, Shahla Abdollahi-Roodsaz, Franco E. Di Padova, Fons A. van de Loo, John Dulos, Wim B. van den Berg and Annemieke M. H. Boots

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34352

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      Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance (pages 1771–1779)

      Fabienne Niederer, Michelle Trenkmann, Caroline Ospelt, Emmanuel Karouzakis, Michel Neidhart, Joanna Stanczyk, Christoph Kolling, Renate E. Gay, Michael Detmar, Steffen Gay, Astrid Jüngel and Diego Kyburz

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34334

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      Methotrexate increases expression of cell cycle checkpoint genes via JNK activation (pages 1780–1789)

      Charles F. Spurlock III, John T. Tossberg, Howard A. Fuchs, Nancy J. Olsen and Thomas M. Aune

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34342

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      The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells (pages 1790–1798)

      Keisuke Maeshima, Kunihiro Yamaoka, Satoshi Kubo, Kazuhisa Nakano, Shigeru Iwata, Kazuyoshi Saito, Masanobu Ohishi, Hisaaki Miyahara, Shinya Tanaka, Koji Ishii, Hironobu Yoshimatsu and Yoshiya Tanaka

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34329

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      CD147 induces angiogenesis through a vascular endothelial growth factor and hypoxia-inducible transcription factor 1α–mediated pathway in rheumatoid arthritis (pages 1818–1827)

      Cong-hua Wang, Hui Yao, Li-na Chen, Jun-feng Jia, Li Wang, Jing-yao Dai, Zhao-hui Zheng, Zhi-nan Chen and Ping Zhu

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34341

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      Proteomic profiling following immunoaffinity capture of high-density lipoprotein: Association of acute-phase proteins and complement factors with proinflammatory high-density lipoprotein in rheumatoid arthritis (pages 1828–1837)

      Junji Watanabe, Christina Charles-Schoeman, Yunan Miao, David Elashoff, Yuen Yin Lee, George Katselis, Terry D. Lee and Srinivasa T. Reddy

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34363

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  6. Experimental Arthritis

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Destructive role of myeloid differentiation factor 88 and protective role of TRIF in interleukin-17–dependent arthritis in mice (pages 1838–1847)

      Shahla Abdollahi-Roodsaz, Fons A. J. van de Loo, Marije I. Koenders, Monique M. Helsen, Birgitte Walgreen, Liduine A. van den Bersselaar, Onno J. Arntz, Nozomi Takahashi, Leo A. B. Joosten and Wim B. van den Berg

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34328

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      Role of transient receptor potential vanilloid 4 in rat joint inflammation (pages 1848–1858)

      Alexandre Denadai-Souza, Laurence Martin, Marco A. Vieira de Paula, Maria C. Werneck de Avellar, Marcelo N. Muscará, Nathalie Vergnolle and Nicolas Cenac

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34345

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  7. Spondylarthritis

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Increased numbers of CD5+ B lymphocytes with a regulatory phenotype in spondylarthritis (pages 1859–1868)

      Tineke Cantaert, Marieke E. Doorenspleet, Gabriela FrancoSalinas, Jaqueline E. Paramarta, Paul L. Klarenbeek, Yvonne Tiersma, Chris M. van der Loos, Niek De Vries, Paul Peter Tak and Dominique L. Baeten

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34364

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      Interleukin-22 and interleukin-22–producing NKp44+ natural killer cells in subclinical gut inflammation in ankylosing spondylitis (pages 1869–1878)

      Francesco Ciccia, Antonina Accardo-Palumbo, Riccardo Alessandro, Aroldo Rizzo, Simona Principe, Sergio Peralta, Francesca Raiata, AnnaRita Giardina, Giacomo De Leo and Giovanni Triolo

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34355

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  8. Psoriatic Arthritis

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Association between systemic antipsoriatic drugs and cardiovascular risk in patients with psoriasis with or without psoriatic arthritis: A nationwide cohort study (pages 1879–1887)

      Yi-Ju Chen, Yun-Ting Chang, Jui-Lung Shen, Tzu-Ting Chen, Chang-Bi Wang, Chuan-Mu Chen and Chun-Ying Wu

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34335

  9. Osteoarthritis

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Risk factors for magnetic resonance imaging–detected patellofemoral and tibiofemoral cartilage loss during a six-month period: The Joints On Glucosamine study (pages 1888–1898)

      Frank W. Roemer, C. Kent Kwoh, Michael J. Hannon, Stephanie M. Green, John M. Jakicic, Robert Boudreau, Michel D. Crema, Carolyn E. Moore and Ali Guermazi

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34353

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      Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis (pages 1899–1908)

      LiQin Xie, Angela S. P. Lin, Kousik Kundu, Marc E. Levenston, Niren Murthy and Robert E. Guldberg

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34370

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      The expression and function of microRNAs in chondrogenesis and osteoarthritis (pages 1909–1919)

      Tracey E. Swingler, Guy Wheeler, Virginia Carmont, Hannah R. Elliott, Matthew J. Barter, Muhammad Abu-Elmagd, Simon T. Donell, Raymond P. Boot-Handford, Mohammad K. Hajihosseini, Andrea Münsterberg, Tamas Dalmay, David A. Young and Ian M. Clark

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34314

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      Autophagy modulates osteoarthritis-related gene expression in human chondrocytes (pages 1920–1928)

      Hiroshi Sasaki, Koji Takayama, Takehiko Matsushita, Kazunari Ishida, Seiji Kubo, Tomoyuki Matsumoto, Norifumi Fujita, Shinya Oka, Masahiro Kurosaka and Ryosuke Kuroda

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34323

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  10. Cartilage Biology

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Inhibiting calcineurin activity under physiologic tonicity elevates anabolic but suppresses catabolic chondrocyte markers (pages 1929–1939)

      Anna E. van der Windt, Esther Haak, Nicole Kops, Jan A. N. Verhaar, Harrie Weinans and Holger Jahr

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34369

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      Perturbation of nuclear lamin A causes cell death in chondrocytes (pages 1940–1949)

      Mukundan Attur, Ami Ben-Artzi, Qing Yang, Hayf E. Al-Mussawir, Howard J. Worman, Glyn Palmer and Steven B. Abramson

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34360

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  11. Disc Disease

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      The pathophysiologic role of the protein kinase Cδ pathway in the intervertebral discs of rabbits and mice: In vitro, ex vivo, and in vivo studies (pages 1950–1959)

      Michael B. Ellman, Jae-Sung Kim, Howard S. An, Jeffrey S. Kroin, Xin Li, Di Chen, Dongyao Yan, Doug D. Buechter, Keiichi Nakayama, Bo Liu, Stephanie Morgan and Hee-Jeong Im

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34337

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      Corrected by:

      Erratum: Incorrect Panel in Figure 3 of the Article by Ellman et al (Arthritis Rheum, June 2012)

      Vol. 68, Issue 12, 2935, Version of Record online: 28 NOV 2016

  12. Systemic Lupus Erythematosus

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Evaluation of TRAF6 in a large multiancestral lupus cohort (pages 1960–1969)

      Bahram Namjou, Chan-Bum Choi, Isaac T. W. Harley, Marta E. Alarcón-Riquelme, BIOLUPUS Network, Jennifer A. Kelly, Stuart B. Glenn, Joshua O. Ojwang, Adam Adler, Kwangwoo Kim, Caroline J. Gallant, Susan A. Boackle, Lindsey A. Criswell, Robert P. Kimberly, Elizabeth E. Brown, Jeffrey Edberg, Graciela S. Alarcón, Anne M. Stevens, Chaim O. Jacob, Gary S. Gilkeson, Diane L. Kamen, Betty P. Tsao, Juan-Manuel Anaya, Eun-Mi Kim, So-Yeon Park, Yoon-Kyoung Sung, Joel M. Guthridge, Joan T. Merrill, Michelle Petri, Rosalind Ramsey-Goldman, Luis M. Vilá, Timothy B. Niewold, Javier Martin, Bernardo A. Pons-Estel, Genoma en Lupus Network, Timothy J. Vyse, Barry I. Freedman, Kathy L. Moser, Patrick M. Gaffney, Adrienne H. Williams, Mary E. Comeau, John D. Reveille, Changwon Kang, Judith A. James, R. Hal Scofield, Carl D. Langefeld, Kenneth M. Kaufman, John B. Harley and Sang-Cheol Bae

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34361

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  13. Systemic Sclerosis

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Brief Report: Successful pregnancies but a higher risk of preterm births in patients with systemic sclerosis: An Italian multicenter study (pages 1970–1977)

      Mara Taraborelli, Véronique Ramoni, Antonio Brucato, Paolo Airò, Gianluigi Bajocchi, Francesca Bellisai, Domenico Biasi, Jelena Blagojevic, Valentina Canti, Roberto Caporali, Paola Caramaschi, Ilaria Chiarolanza, Veronica Codullo, Franco Cozzi, Giovanna Cuomo, Maurizio Cutolo, Maria De Santis, Salvatore De Vita, Emma Di Poi, Andrea Doria, Paola Faggioli, Maria Favaro, Gianfranco Ferraccioli, Clodoveo Ferri, Rosario Foti, Alessandro Gerosa, Maria Gerosa, Sarah Giacuzzo, Leopoldo Giani, Dilia Giuggioli, Massimo Imazio, Michele Iudici, Annamaria Iuliano, Roberto Leonardi, Massimiliano Limonta, Andrea Lojacono, Chiara Lubatti, Marco Matucci-Cerinic, Antonino Mazzone, Marianna Meroni, Pier Luigi Meroni, Marta Mosca, Mario Motta, Marina Muscarà, Simona Nava, Melissa Padovan, Giorgio Pagani, Giuseppe Paolazzi, Susanna Peccatori, Viviana Ravagnani, Valeria Riccieri, Edoardo Rosato, Patrizia Rovere-Querini, Felice Salsano, Alessandro Santaniello, Raffaella Scorza, Chiara Tani, Gabriele Valentini, Guido Valesini, Massimo Vanoli, Barbara Vigone, Silvana Zeni, Angela Tincani and on behalf of the IMPRESS Investigators

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34350

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      Effect of oxidative stress on protein tyrosine phosphatase 1B in scleroderma dermal fibroblasts (pages 1978–1989)

      Pei-Suen Tsou, Nadine N. Talia, Adam J. Pinney, Ann Kendzicky, Sonsoles Piera-Velazquez, Sergio A. Jimenez, James R. Seibold, Kristine Phillips and Alisa E. Koch

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34336

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      Sunitinib inhibits the phosphorylation of platelet-derived growth factor receptor β in the skin of mice with scleroderma-like features and prevents the development of the disease (pages 1990–2000)

      Niloufar Kavian, Amélie Servettaz, Wioleta Marut, Carole Nicco, Christiane Chéreau, Bernard Weill and Frédéric Batteux

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34354

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  14. Vasculitis

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Interleukin-21 modulates Th1 and Th17 responses in giant cell arteritis (pages 2001–2011)

      Benjamin Terrier, Guillaume Geri, Wahiba Chaara, Yves Allenbach, Michelle Rosenzwajg, Nathalie Costedoat-Chalumeau, Pierre Fouret, Lucile Musset, Olivier Benveniste, Adrien Six, David Klatzmann, David Saadoun and Patrice Cacoub

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34327

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  15. Pediatric Rheumatology

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
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      Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis (pages 2012–2021)

      Carol A. Wallace, Edward H. Giannini, Steven J. Spalding, Philip J. Hashkes, Kathleen M. O'Neil, Andrew S. Zeft, Ilona S. Szer, Sarah Ringold, Hermine I. Brunner, Laura E. Schanberg, Robert P. Sundel, Diana Milojevic, Marilynn G. Punaro, Peter Chira, Beth S. Gottlieb, Gloria C. Higgins, Norman T. Ilowite, Yukiko Kimura, Stephanie Hamilton, Anne Johnson, Bin Huang, Daniel J. Lovell and for the Childhood Arthritis and Rheumatology Research Alliance

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34343

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      Brief Report: Genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne) (pages 2022–2027)

      Andrew P. Demidowich, Alexandra F. Freeman, Douglas B. Kuhns, Ivona Aksentijevich, John I. Gallin, Maria L. Turner, Daniel L. Kastner and Steven M. Holland

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34332

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  16. Pain

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      A systematic review of the global prevalence of low back pain (pages 2028–2037)

      Damian Hoy, Christopher Bain, Gail Williams, Lyn March, Peter Brooks, Fiona Blyth, Anthony Woolf, Theo Vos and Rachelle Buchbinder

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34347

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      Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model (pages 2038–2047)

      Anna K. Clark, John Grist, Adam Al-Kashi, Mauro Perretti and Marzia Malcangio

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34351

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  17. Concise Communication

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
  18. Clinical Images

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Yellowish, thick, creamy synovial fluid in a joint effusion (page 2050)

      Roberta Maggio, Marco Bardelli, Valentina Di Sabatino and Giacomo Maria Guidelli

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34432

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  19. Letter

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
    2. You have free access to this content
    3. You have free access to this content
      Reply (pages 2053–2054)

      Chaim O. Jacob and William Stohl

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34387

  20. Clinical Images

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      Lipoma arborescens (page 2054)

      P. Diana Afonso

      Version of Record online: 25 MAY 2012 | DOI: 10.1002/art.34462

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  21. ACR Announcements

    1. Top of page
    2. In This Issue
    3. Review
    4. Editorial
    5. Unresolved Questions in Rheumatology
    6. Rheumatoid Arthritis
    7. Experimental Arthritis
    8. Spondylarthritis
    9. Psoriatic Arthritis
    10. Osteoarthritis
    11. Cartilage Biology
    12. Disc Disease
    13. Systemic Lupus Erythematosus
    14. Systemic Sclerosis
    15. Vasculitis
    16. Pediatric Rheumatology
    17. Pain
    18. Concise Communication
    19. Clinical Images
    20. Letter
    21. Clinical Images
    22. ACR Announcements
    1. You have free access to this content
      ACR Announcements

      Version of Record online: 29 MAY 2012 | DOI: 10.1002/art.34532

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