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Keywords:

  • adamantane;
  • branched DNA;
  • DNA;
  • oligonucleotides;
  • self-assembly

Abstract

DNA governs the storage and transfer of genetic information through generations in all living systems with the exception of some viruses. Its physicochemical nature and the Watson–Crick base pairing properties allow molecular constructions at nanometer length, thereby enabling the design of desired structural motifs, which can self-assemble to form large supramolecular arrays and scaffolds. The tailor-made DNAs have been an interesting material for such designed nanoscale constructions. However, the synthesis of specific structures with a desired molecular function is still in its infancy and therefore has to be further explored. To add a new dimension to this approach, we have synthesized a rigid three-way branched adamantane motif, which is capable of forming highly stable DNA networks. The moiety generated could serve as a useful building block for DNA-based nanoconstructions.

Featured Compounds

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  1. 1 - 9
Compound 1
Molecular Weight:136.234
Molecular Formula:C10H16
InChIKey:ORILYTVJVMAKLC-UHFFFAOYSA-N
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Compound 4
Molecular Weight:208.2982
Molecular Formula:C16H16
InChIKey:Not Available
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Compound 6
Molecular Weight:476.521
Molecular Formula:C27H28N2O6
InChIKey:Not Available
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Compound 5
Molecular Weight:396.1352
Molecular Formula:C11H13IN2O6
InChIKey:Not Available
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Compound 7
Molecular Weight:698.5016
Molecular Formula:C32H31IN2O8
InChIKey:Not Available
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Compound 8
Molecular Weight:1617.6993
Molecular Formula:C91H88N6O22
InChIKey:Not Available
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Compound 9
Molecular Weight:1817.9174
Molecular Formula:C100H105N8O23P
InChIKey:Not Available
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Compound 2
Molecular Weight:372.922
Molecular Formula:C10H13Br3
InChIKey:Not Available
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Compound 3
Molecular Weight:693.77
Molecular Formula:C16H22Br6
InChIKey:Not Available
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  1. 1 - 9