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Keywords:

  • chemokine;
  • peptides;
  • receptors;
  • solid-phase synthesis;
  • sulfation
Thumbnail image of graphical abstract

On solid ground: A solid-phase strategy for the efficient synthesis of sulfopeptides is described. Selective deprotection of orthogonally-protected tyrosine residues and solid-phase sulfation provided divergent access to differentially sulfated peptides in high yields.

Featured Compounds

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  1. 1 - 28
Compound 1
Molecular Weight:517.6881
Molecular Formula:C30H35NO5Si
InChIKey:CQIORESQZRVISK-MHZLTWQESA-N
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Compound 2
Molecular Weight:443.4911
Molecular Formula:C27H25NO5
InChIKey:AQUXDQFCBLRIRE-VWLOTQADSA-N
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Compound 3
Molecular Weight:395.395
Molecular Formula:C7H10BCl3F4N2O3S
InChIKey:MBOCBWMSNLXDKF-UHFFFAOYSA-N
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Compound 4
Molecular Weight:358.934
Molecular Formula:C7H9BCl2F4N2O3S
InChIKey:YFRLPAAPNPXKQQ-UHFFFAOYSA-N
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Compound 5
Molecular Weight:1106.3623
Molecular Formula:C55H81N8O14Si
InChIKey:Not Available
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Compound 6
Molecular Weight:840.8329
Molecular Formula:C38H48N8O14
InChIKey:NKSSAFBQMYCONW-IUBBXRRTSA-N
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Compound 7a
Molecular Weight:1052.284
Molecular Formula:C40H49Cl3N8O17S
InChIKey:SFWKYPIYRCOKDN-NNQQVJEXSA-N
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Compound 7b
Molecular Weight:1015.824
Molecular Formula:C40H48Cl2N8O17S
InChIKey:FAGXKTBULHXHNE-NNQQVJEXSA-N
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Compound 8a
Molecular Weight:1052.284
Molecular Formula:C40H49Cl3N8O17S
InChIKey:WEZSUZHWHMZGIG-NNQQVJEXSA-N
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Compound 8b
Molecular Weight:1015.824
Molecular Formula:C40H48Cl2N8O17S
InChIKey:ZGUDLALARNKBEQ-NNQQVJEXSA-N
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Compound 9a
Molecular Weight:1263.736
Molecular Formula:C42H50Cl6N8O20S2
InChIKey:UNKLOBYJEHOMJG-RBKWUFDTSA-N
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Compound 9b
Molecular Weight:1190.814
Molecular Formula:C42H48Cl4N8O20S2
InChIKey:GIVKMEFNJACHOE-RBKWUFDTSA-N
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Compound 10
Molecular Weight:937.927
Molecular Formula:C38H51N9O17S
InChIKey:UAENSYBTCHHCFJ-LSBHLDBLSA-N
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Compound 11
Molecular Weight:937.927
Molecular Formula:C38H51N9O17S
InChIKey:WKJFILDHESAWRH-LSBHLDBLSA-N
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Compound 12
Molecular Weight:1053.059
Molecular Formula:C38H57N11O20S2
InChIKey:KERSGSFLRCZALD-MDSJQLFGSA-O
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Compound 13
Molecular Weight:2142.6653
Molecular Formula:C110H166N15O26Si
InChIKey:Not Available
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Compound 14
Molecular Weight:1652.7107
Molecular Formula:C77H101N15O26
InChIKey:XUZWNBDHTDQZCO-OTQOBNGPSA-N
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Compound 15
Molecular Weight:1864.162
Molecular Formula:C79H102Cl3N15O29S
InChIKey:HVNZWXCVAYWQHH-GAGCDHCPSA-N
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Compound 16
Molecular Weight:1864.162
Molecular Formula:C79H102Cl3N15O29S
InChIKey:PIJQZBKWDIXXMQ-GAGCDHCPSA-N
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Compound 17
Molecular Weight:2075.614
Molecular Formula:C81H103Cl6N15O32S2
InChIKey:DZNJJVFRJQQZTR-IOESENBDSA-N
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Compound 18
Molecular Weight:1749.804
Molecular Formula:C77H104N16O29S
InChIKey:BMIVUPAKZQHCOV-KGDQCYTHSA-N
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Compound 19
Molecular Weight:1749.804
Molecular Formula:C77H104N16O29S
InChIKey:CZHNMVRIBPJLCW-KGDQCYTHSA-N
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Compound 20
Molecular Weight:1846.898
Molecular Formula:C77H107N17O32S2
InChIKey:QSZWAXQROPGPGO-LNYNQGBHSA-N
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Compound 21
Molecular Weight:2294.565
Molecular Formula:C99H152N28O31S2
InChIKey:ABOAVZPKVYQAFG-RXIDBDSQSA-N
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Compound 22
Molecular Weight:3590.841
Molecular Formula:C156H233N43O53S
InChIKey:WSMLNOUMSQOYEG-AEESLPEHSA-N
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Compound 23
Molecular Weight:3687.934
Molecular Formula:C156H236N44O56S2
InChIKey:BKMDUBPCFHOEIW-CWTXVZGQSA-N
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Compound 24
Molecular Weight:3687.934
Molecular Formula:C156H236N44O56S2
InChIKey:NOCDPFRQAYKFCL-CWTXVZGQSA-N
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Compound 25
Molecular Weight:3785.028
Molecular Formula:C156H239N45O59S3
InChIKey:DETLNHGORFHHFH-RBMPWVNJSA-N
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  1. 1 - 28