Communication

Palladium-Catalyzed Carbonylative Negishi-type Coupling of Aryl Iodides with Benzyl Chlorides

  1. Xiao-Feng Wu,
  2. Johannes Schranck,
  3. Dr. Helfried Neumann,
  4. Prof. Dr. Matthias Beller*

Article first published online: 11 OCT 2011

DOI: 10.1002/asia.201100627

Issue

Chemistry – An Asian Journal

Chemistry – An Asian Journal

Volume 7, Issue 1, pages 40–44, January 2, 2012

Additional Information

How to Cite

Wu, X.-F., Schranck, J., Neumann, H. and Beller, M. (2012), Palladium-Catalyzed Carbonylative Negishi-type Coupling of Aryl Iodides with Benzyl Chlorides. Chem. Asian J., 7: 40–44. doi: 10.1002/asia.201100627

Author Information

  1. Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-5000

*Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059 Rostock (Germany), Fax: (+49) 381-1281-5000

Publication History

  1. Issue published online: 22 DEC 2011
  2. Article first published online: 11 OCT 2011
  3. Manuscript Revised: 21 AUG 2011
  4. Manuscript Received: 18 JUL 2011

Funded by

  • Bundesministerium für Bildung und Forschung (BMBF)

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Keywords:

  • 1,2-diarylethanones;
  • benzyl chlorides;
  • carbonylation;
  • Negishi coupling;
  • palladium
Thumbnail image of graphical abstract

Do the competition: The synthesis of 1,2-diarylethanones has been accomplished using the palladium-catalyzed coupling of aryl iodides and CO/benzyl chlorides or benzoyl chlorides. These reactions proceed smoothly in the presence of zinc powder to afford the products in moderate to excellent yields.

Featured Compounds

Compound 1
Molecular Weight:196.2445
Molecular Formula:C14H12O
InChIKey:OTKCEEWUXHVZQI-UHFFFAOYSA-N
View compound in article | Full details | Search this compound
Compound 2
Molecular Weight:182.261
Molecular Formula:C14H14
InChIKey:QWUWMCYKGHVNAV-UHFFFAOYSA-N
View compound in article | Full details | Search this compound
Compound 3
Molecular Weight:210.2711
Molecular Formula:C15H14O
InChIKey:YFKBXYGUSOXJGS-UHFFFAOYSA-N
View compound in article | Full details | Search this compound
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