Communication

Reaction-Based Two-Photon Fluorescent Probe for Turn-On Mercury(II) Sensing and Imaging in Live Cells

  1. Rong Huang1,†,
  2. Xiaolong Zheng1,†,
  3. Changcheng Wang1,
  4. Renyi Wu3,
  5. Shengyong Yan1,
  6. Jiaqi Yuan1,
  7. Prof. Xiaocheng Weng1,
  8. Prof. Dr. Xiang Zhou1,2,*

Article first published online: 9 FEB 2012

DOI: 10.1002/asia.201101028

Issue

Chemistry – An Asian Journal

Chemistry – An Asian Journal

Volume 7, Issue 5, pages 915–918, May 2012

Additional Information

How to Cite

Huang, R., Zheng, X., Wang, C., Wu, R., Yan, S., Yuan, J., Weng, X. and Zhou, X. (2012), Reaction-Based Two-Photon Fluorescent Probe for Turn-On Mercury(II) Sensing and Imaging in Live Cells. Chem. Asian J., 7: 915–918. doi: 10.1002/asia.201101028

Author Information

  1. 1

    College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, State Key Laboratory of Virology, Wuhan University, Hubei, Wuhan, 430072 (P. R. China), Fax: (+86) 27-87336380

  2. 2

    State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, 100871 (P. R. China)

  3. 3

    Institute of Zoology, Chinese Academy of Science, Beijing, 100101 (P. R. China)

  1. †

    These authors contributed equally to this work.

*College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, State Key Laboratory of Virology, Wuhan University, Hubei, Wuhan, 430072 (P. R. China), Fax: (+86) 27-87336380

Publication History

  1. Issue published online: 26 APR 2012
  2. Article first published online: 9 FEB 2012
  3. Manuscript Received: 19 DEC 2011

Funded by

  • National Basic Research Program of China. Grant Numbers: 2012CB720600, 2012CB720603
  • National Science Foundation of China. Grant Numbers: 90813031, 21072115, 30973605, 21102108, 20802055
  • Chinese Academy of Sciences

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Keywords:

  • fluorescent probes;
  • mercury;
  • microscopy;
  • sensors
Thumbnail image of graphical abstract

Shine on: In this mercury(II) sensing approach, the non-fluorescent probe SAN undergoes Hg2+-promoted deprotection reaction, resulting in the formation of the two-photon-fluorescent product AAN. The system shows high sensitivity and selectivity and also can be used in live-cell environments.

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