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Keywords:

  • analog;
  • ligand–protein interaction;
  • nonspecific binding;
  • photoaffinity labeling;
  • proteins
Thumbnail image of graphical abstract

Two are better than one: A new approach to selective photoaffinity labeling is described in which a bioactive probe is used in combination with its inactive analog as a scavenger of nonspecific proteins.

Featured Compounds

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  1. 1 - 13
Compound 1
Molecular Weight:862.069
Molecular Formula:C43H55N7O8S2
InChIKey:VMAPPQJRLOTMQT-RKGRWMRJSA-N
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Compound 2
Molecular Weight:813.016
Molecular Formula:C44H56N6O7S
InChIKey:HHUACJHMYSYHQB-QEKRTFLRSA-N
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Compound 3
Molecular Weight:818.958
Molecular Formula:C40H46N6O9S2
InChIKey:URXPCGROCGOWQA-DHUJRADRSA-N
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Compound 4
Molecular Weight:720.8531
Molecular Formula:C42H48N4O7
InChIKey:BTGROIOSZPXFEK-QNGWXLTQSA-N
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Compound 5
Molecular Weight:246.3034
Molecular Formula:C11H22N2O4
InChIKey:DQUHYEDEGRNAFO-QMMMGPOBSA-N
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Compound 6
Molecular Weight:323.2995
Molecular Formula:C18H13NO5
InChIKey:MVQNJLJLEGZFGP-UHFFFAOYSA-N
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Compound 7
Molecular Weight:454.5155
Molecular Formula:C25H30N2O6
InChIKey:LXUTZRDACUDANT-FQEVSTJZSA-N
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Compound 8
Molecular Weight:342.5
Molecular Formula:C16H30N4O2S
InChIKey:QWVNTBHBRBLRRJ-OWYJLGKBSA-N
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Compound 9
Molecular Weight:779
Molecular Formula:C41H58N6O7S
InChIKey:AZOALBAWGHIOOA-ULZMUIMWSA-N
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Compound 10
Molecular Weight:216.3205
Molecular Formula:C11H24N2O2
InChIKey:RVZPDKXEHIRFPM-UHFFFAOYSA-N
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Compound 11
Molecular Weight:652.8207
Molecular Formula:C36H52N4O7
InChIKey:MUNUVSHRTCVYHB-LJAQVGFWSA-N
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Compound 15
Molecular Weight:152.1473
Molecular Formula:C8H8O3
InChIKey:ZEYHEAKUIGZSGI-UHFFFAOYSA-N
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Compound 14
Molecular Weight:226.2274
Molecular Formula:C14H10O3
InChIKey:IFQUPKAISSPFTE-UHFFFAOYSA-N
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  1. 1 - 13