Surface-Initiated, Reversible Polymerization from Surface-Tethered Oligonucleotides by Enzymatic Processes

Authors

  • Prof. Dr. Jungkyu K. Lee,

    1. Department of Chemistry, Kyungpook National University, Daegu 702-701 (Korea), Fax: (+82) 53-950-6330
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  • Mi Rae Kim,

    1. Molecular-Level Interface Research Center, Department of Chemistry, KAIST, Daejeon 305-701 (Korea), Fax: (+82) 42-350-2810
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  • Prof. Dr. Insung S. Choi,

    Corresponding author
    1. Molecular-Level Interface Research Center, Department of Chemistry, KAIST, Daejeon 305-701 (Korea), Fax: (+82) 42-350-2810
    • Insung S. Choi, Molecular-Level Interface Research Center, Department of Chemistry, KAIST, Daejeon 305-701 (Korea), Fax: (+82) 42-350-2810

      Yang-Gyun Kim, Department of Chemistry, Sungkyunkwan University, Suwon 440-746 (Korea), Fax: (+82) 31-290-4574

      Young Hwan Jung, Department of BioNanomaterials, Bio-Campus of Korea Polytechnic, Chung-nam 320-905 (Korea), Fax: (+82) 41-746-7368

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  • Prof. Dr. Yang-Gyun Kim,

    Corresponding author
    1. Department of Chemistry, Sungkyunkwan University, Suwon 440-746 (Korea), Fax: (+82) 31-290-4574
    • Insung S. Choi, Molecular-Level Interface Research Center, Department of Chemistry, KAIST, Daejeon 305-701 (Korea), Fax: (+82) 42-350-2810

      Yang-Gyun Kim, Department of Chemistry, Sungkyunkwan University, Suwon 440-746 (Korea), Fax: (+82) 31-290-4574

      Young Hwan Jung, Department of BioNanomaterials, Bio-Campus of Korea Polytechnic, Chung-nam 320-905 (Korea), Fax: (+82) 41-746-7368

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  • Prof. Dr. Young Hwan Jung

    Corresponding author
    1. Department of BioNanomaterials, Bio-Campus of Korea Polytechnic, Chung-nam 320-905 (Korea), Fax: (+82) 41-746-7368
    • Insung S. Choi, Molecular-Level Interface Research Center, Department of Chemistry, KAIST, Daejeon 305-701 (Korea), Fax: (+82) 42-350-2810

      Yang-Gyun Kim, Department of Chemistry, Sungkyunkwan University, Suwon 440-746 (Korea), Fax: (+82) 31-290-4574

      Young Hwan Jung, Department of BioNanomaterials, Bio-Campus of Korea Polytechnic, Chung-nam 320-905 (Korea), Fax: (+82) 41-746-7368

    Search for more papers by this author

Abstract

original image

Back and forth: Enzymatic, reversible polymerization on gold surfaces was efficiently carried out from surface-tethered self-priming oligodeoxynucleotides in a sequence-specific fashion by using two kinds of enzymes. Taq DNA polymerase, acting as a catalyst, facilitated DNA polymerization, and DNA restriction enzymes cut DNA polymers from the surface.

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