Synthesis and Cytotoxicity of Dendritic Platinum Nanoparticles with HEK-293 Cells (pages 21–26)
Kyubin Shim, Dr. Jeonghun Kim, Prof. Yoon-Uk Heo, Bo Jiang, Dr. Cuiling Li, Prof. Mohammed Shahabuddin, Prof. Kevin C.-W. Wu, Dr. Md. Shahriar A. Hossain, Prof. Yusuke Yamauchi and Prof. Jung Ho Kim
Version of Record online: 2 DEC 2016 | DOI: 10.1002/asia.201601239
Not Toxic! Dendritic platinum nanoparticles (DPNs) have been synthesized via a sonochemical method. The particle size and shape of the DPNs could be tuned by changing the reduction temperature, resulting in a uniform DPN with a size of 23 nm or 60 nm. The cytotoxicity of DPNs was investigated using HEK-293 human embryonic kidney cells, and the biological adaptability exhibited by DPNs has opened a pathway to biomedical applications.