Cover Picture: Sugar-Decorated Dendritic Nanocarriers: Encapsulation and Release of the Octahedral Rhenium Cluster Complex [Re6S8(OH)6]4− (Chem. Asian J. 12/2010) (page 2429)
Manja Kubeil, Dr. Holger Stephan, Dr. Hans-Jürgen Pietzsch, Dr. Gerhard Geipel, Dr. Dietmar Appelhans, Prof. Dr. Brigitte Voit, Jan Hoffmann, Prof. Dr. Bernhard Brutschy, Dr. Yuri V. Mironov, Dr. Konstantin A. Brylev and Prof. Dr. Vladimir E. Fedorov
Version of Record online: 1 DEC 2010 | DOI: 10.1002/asia.201090041
Nanomaterials based on a dendritic structure are widely recognized as fascinating drug-delivery vehicles and, owing to their near-perfect architectures and the wide scope for structural variation, such molecules seem to be ideally suited to encapsulate drug molecules. In this context, sugar-decorated dendritic nanocontainers are of special interest. In their Full Paper on page 2507 ff., H. Stephan et al. show that glycodendrimers with dense maltose shells are capable of encapsulating and releasing nanometer-sized guest molecules in a controlled manner. Different physico-chemical methods provide strong evidence that the guest molecules are preferentially bound in the interior of the dendritic skeleton.