Diol Appended Quenchers for Fluorescein Boronic Acid (pages 581–588)
Souad A. Elfeky, Stephen E. Flower, Naoko Masumoto, François D'Hooge, Ludivine Labarthe, Wenbo Chen, Christophe Len, Tony D. James and John S. Fossey
Version of Record online: 1 FEB 2010 | DOI: 10.1002/asia.200900386
Linking it all together! A fluorescein boronic acid derivative was prepared in one step, its interaction with readily prepared bespoke diol appended quenchers was studied revealing enhanced FRET quenching owing to ester formation. The same fluorescent boronic acid also had its fluorescence efficiently quenched by nucleosides through boronate ester formation.