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Appendix S1. Description of SAC and STC families included in the study.

Figure S1. Distribution of SRS scores. Fathers SRS scores: untransformed (left) and square root transformed (right).

Figure S2. Frequencies of transmitted vs. not transmitted CNVs in probands and siblings.

Table S1. List of probands (p1) excluded from the analyses.

Table S2. Inheritance of BP1-BP2 CNV in siblings and probands of ASD families.

Table S3. Transmission of BP1-BP2 CNVs.

Table S4. Effect of CNV on phenotype in parents and siblings estimated from multiple linear regression analysis.

Table S5. Effect of CNV on phenotype in probands estimated from multiple linear regression analysis.

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