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  • Abrahams, B., & Geschwind, D. (2008). Advances in autism genetics: on the threshold of a new neurobiology. Nature Review Genetics, 9, 341355.
  • AGP. (2007). Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nature Genetics, 39, 319328.
  • APA. (1994). DSM-IV diagnostic and statistical manual of mental disorders, 4th Edition. Washington, DC: American Psychiatric Association.
  • Ashley-Koch, A., Mei, H., Jaworski, J., Ma, D., Ritchie, M., et al. (2006). An analysis paradigm for investigating multi-locus effects in complex disease: examination of three GABA A receptor subunit genes on 15q11–q13 as risk factors for autistic disorder. Annals of Human Genetics, 70, 281292.
  • Auyeung, B., Baron-Cohen, S., Chapman, E., Knickmeyer, R., Taylor, K., & Hackett, G. (2006). Foetal testosterone and the child systemizing quotient. European Journal of Endocrinology, 155, 123130.
  • Auyeung, B., Baron-Cohen, S., Ashwin, E., Knickmeyer, R., Taylor, K., & Hackett, G. (2009). Fetal testosterone and autistic traits. British Journal of Psychology, 100, 122.
  • Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simmonoff, E., et al. (1995). Autism as a strongly genetic disorder: evidence from a British twin study. Psychological Medicine, 25, 6377.
  • Baird, G., Simonoff, E., Pickles, A., Chandler, S., Loucas, T., et al. (2006). Prevalence of disorders of the autism spectrum in a population cohort of children in South Thames: the Special Needs and Autism Project (SNAP). The Lancet, 368, 210215.
  • Baron-Cohen, S. (1995). Mindblindness: an essay on autism and theory of mind. Boston: MIT Press/Bradford Books.
  • Baron-Cohen, S., & Hammer, J. (1997). Parents of children with Asperger syndrome: what is the cognitive phenotype? Journal of Cognitive Neuroscience, 9, 548554.
  • Baron-Cohen, S., & Wheelwright, S. (2004). The empathy quotient (EQ). An investigation of adults with Asperger syndrome or high functioning autism, and normal sex differences. Journal of Autism and Developmental Disorders, 34, 163175.
  • Baron-Cohen, Joliffe, T., Mortimore, C., & Robertson, M. (1997). Another advanced test of theory of mind: evidence from very high functioning adults with autism or Asperger Syndrome. Journal of Child Psychology and Psychiatry, 38, 813822.
  • Baron-Cohen, S., Ring, H., Bullmore, E., Wheelwright, S., Ashwin, C., & Williams, S. (2000). The amygdala theory of autism. Neuroscience and Behavioural Reviews, 24, 355364.
  • Baron-Cohen, S., Wheelwright, S., Hill, J., Raste, Y., & Plumb, I. (2001a). The “reading the mind in the eyes” test revised version: a study with normal adults, and adults with Asperger syndrome or high-functioning autism. Journal of Child Psychiatry and Psychiatry, 42, 241252.
  • Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001b). The Autism Spectrum Quotient (AQ): evidence from Asperger syndrome/high functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31, 517.
  • Baron-Cohen, S., Lutchmaya, S., & Knickmeyer, R. (2004). Prenatal testosterone in mind: amniotic fluid studies. Cambridge, MA: MIT/Bradford.
  • Baron-Cohen, S., Knickmeyer, R.C., & Belmonte, M.K. (2005). Sex differences in the brain: implications for explaining autism. Science, 310, 819823.
  • Belmonte, M.K., Allen, G., Beckel-Mitchener, A., Boulanger, L., Carper, R., & Webb, S. (2004). Autism and abnormal development of brain connectivity. Journal of Neuroscience, 24, 92289231.
  • Benayed, R., Gharani, N., Rossman, I., Mancuso, V., Lazar, G., et al. (2005). Support for the homeobox transcription factor gene engrailed 2 as an autism spectrum disorder susceptibility locus. American Journal of Human Genetics, 77, 851868.
  • Billington, J., Baron-Cohen, S., & Wheelwright, S. (2007). Cognitive style predicts entry into physical sciences and humanities: questionnaire and performance tests of empathy and systemizing. Learning and Individual Differences, 17, 260268.
  • Bishop, D., Maybery, M., Maley, A., Wong, D., Hill, W., & Hallmayer, J. (2004). Using self-report to identify the broad phenotype in parents of children with autistic spectrum disorders: a study using the Autism Spectrum Quotient. Journal of Child Psychology and Psychiatry, 45, 14311436.
  • Buxbaum, J.D., Silverman, J., Smith, C.J., Greenberg, D.A., Kilfarski, M., et al. (2002). Association between a GABRB3 polymorphism and autism. Molecular Psychiatry, 7, 311316.
  • Chakrabarti, B., Kent, L., Suckling, J., Bullmore, E.T., & Baron-Cohen, S. (2006). Variations in human cannabinoid receptor (CNR1) gene modulate striatal response to happy faces. European Journal of Neuroscience, 23, 19441948.
  • Champagne, F., Weaver, I., Diorio, J., Dymov, S., Szyf, M., & Meaney, M.J. (2006). Maternal care associated with methylation of the estrogen receptor-alpha1b promoter and estrogen receptor-alpha expression in the medial preoptic area of female offspring. Endocrinology, 147, 29092915.
  • Chapman, E., Baron-Cohen, S., Auyeung, B., Knickmeyer, R., Hackett, G., & Taylor, K. (2006). Foetal testosterone and empathy: evidence from the empathy quotient (EQ) and the “reading the mind in the eyes test”. Social Neuroscience, 1, 135148.
  • Collins, F.S., Guyer, M.S., & Chakravarti, A. (1997). Variations on a theme: cataloging human DNA sequence variation. Science, 278, 15801581.
  • Compagnone, N.A., & Mellon, S.H. (1998). Dehydroepiandrosterone: a potential signalling molecule for neocortical organisation during development. Proceedings of National Academy of Science USA, 95, 46784683.
  • Conciatori, M., Stodgell, C., Hyman, S., O'Bara, M., Militerni, R., et al. (2004). Association between the HOXA1 A218G polymorphism and increased head circumference in patients with autism. Biological Psychiatry, 55, 413419.
  • Constantino, J., & Todd, R. (2005). Intergenerational transmission of subthreshold autistic traits in the general population. Biological Psychiatry, 57, 655660.
  • Dawson, G., Carver, L.J., Meltzoff, A.N., Panagiotides, H., McPartland, J., & Webb, S.J. (2002). Neural correlates of face and object recognition in young children with autism spectrum disorder, developmental delay and typical development. Child Development, 73, 700717.
  • Da Silva, J.S., Hasegawa, T., Miyagi, T., Dotti, C.G., & Abad-Rodriguez, J. (2005). Asymmetric membrane ganglioside sialidase activity specifies axonal fate. Nature Neuroscience, 8, 544546.
  • De Vries, G., Rissman, E., Simerley, R.B., Yang, L., Scordalakes, E.M., et al. (2002). A model system for study of sex chromosome effects on sexually dimorphic neural and behavioural traits. The Journal of Neuroscience, 22, 90059014.
  • DeLorey, T.M., Sahbaie, P., Hashemi, E., Homanics, G.E., & Clark, J.D. (2007). Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder. Behavioural Brain Research, 187, 207220.
  • Dewing, P., Shi, T., Horvath, S., & Vilian, E. (2003). Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation. Molecular Brain Research, 118, 8290.
  • Di Cristo, G. (2007). Development of cortical GABAergic circuits and its implications for neurodevelopmental disorders. Clinical Genetics, 72, 18.
  • Dorris, L., Espie, C.A.E., Knott, F., & Salt, J. (2004). Mindreading difficulties in the siblings of people with Asperger's syndrome: evidence for a genetic influence in the abnormal development of a specific cognitive domain. Journal of Child Psychology and Psychiatry, 45, 412418.
  • Domes, G., Heinrichs, M., Michel, A., Berger, C., & Herpertz, S.C. (2007). Oxytocin improves mindreading in humans. Biological Psychiatry, 61, 731733.
  • Dudbridge, F. (2008). Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Human Heredity, 66, 8998.
  • Edwin, J.C.G.v.d.O. (2008). Controlling false discoveries in genetic studies. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 147B, 637644.
  • File, S.E., & Seth, P. (2003). A review of 25 years of the social interaction test. European Journal of Pharmacology, 463, 3553.
  • Gillberg, C. (1991). Clinical and neurobiological aspects of Asperger syndrome in six family studies. In: Frith, U., editor. Autism and Asperger syndrome. Cambridge: Cambridge University Press.
  • Good, C.D., Lawrence, K., Simon-Thomas, N., Price, C.J., Ashburner, J., et al. (2003). Dosage-sensitive X-linked locus influences the development of amygdala and obitofrontal cortex, and fear recognition in humans. Brain, 126, 116.
  • Grimsby, J., Toth, M., Chen, K., Kumazawa, T., Klaidman, L., et al. (1997). Increased stress response and bold beta-phenylethylamine in MAOB-deficient mice. Nature Genetics, 17, 206210.
  • Han, T., & De Vries, G. (2003). Organizational effects of testosterone, estradiol, and dihydrotestosterone on vasopressin mRNA expression in the bed nucleus of the stria terminalis. Journal of Neurobiology, 54, 502510.
  • Hoekstra, R., Bartels, M., Verweij, C., & Boomsma, D. (2007). Heritability of autistic traits in the general population. Archives of Pediatric and Adolescent Medicine, 161, 372377.
  • Hollander, E., Novotny, S., Hanratty, M., Yaffe, R., DeCaria, C., et al. (2003). Oxytocin infusion reduces repetitive behaviors in adults with autistic and Asperger's disorders. Neuropsychopharmacology, 28, 193198.
  • Hu, V.W., Nguyen, A., Kim, K.S., Steinberg, M.E., Sarachana, T., Scully, M.A., et al. (2009). Gene expression profiling of lymphoblasts from autistic and nonaffected sib pairs: altered pathways in neuronal development and steroid biosynthesis. PLoS ONE, 4, e5775.
  • ICD-10. 1994. International classification of diseases. Geneva, Switzerland: World Health Organisation.
  • ICD-10. 1994. International classification of diseases. Geneva, Switzerland: World Health Organisation.
  • Ingudomnukul, E., Baron-Cohen, S., Wheelwright, S., & Knickmeyer, R. (2007). Elevated rates of testosterone-related disorders in women with autism spectrum conditions. Hormones and Behavior, 51, 597604.
  • Insel, T., O'Brien, D., & Leckman, J. (1999). Oxytocin, vasopressin, and autism: is there a connection? Biological Psychiatry, 45, 145157.
  • Jamain, S., Quach, H., Betancur, C., et al. (2003). Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nature, 34, 2729.
  • Jolliffe, T., & Baron-Cohen, S. (1997). Are people with autism or Asperger's syndrome faster than normal on the embedded figures task? Journal of Child Psychology and Psychiatry, 38, 527534.
  • Knickmeyer, R., Baron-Cohen, S., Raggatt, P., & Taylor, K. (2005). Foetal testosterone, social cognition, and restricted interests in children. Journal of Child Psychology and Psychiatry, 46, 198210.
  • Koido, K., Kõks, S., Nikopensius, T., Maron, E., Altmäe, S., et al. (2004). Polymorphisms in wolframin (WFS1) gene are possibly related to increased risk for mood disorders. The International Journal of Neuropsychopharmacology, 8, 235244.
  • Kosfeld, M., Heinrichs, M., Zak, P.J., Fischbacher, U., & Fehr, E. (2005). Oxytocin increases trust in humans. Nature, 435, 673676.
  • Kudwa, A. E., Bodo, C., Gustafsson, J.A., & Rissman, E.F. (2005). A previously uncharacterized role for estrogen receptor {beta}: defeminization of male brain and behavior. Proceedings of the National Academy of Sciences USA, 102, 4608.
  • Kuribayashi, I., Nomoto, S., Massa, G., Oostdijk, W., Wit, J., et al. (2005). Steroid 11-beta-hydroxylase deficiency caused by compound heterozygosity for a novel mutation, p G314R, in one CYP11B1 allele, and a chimeric CYP11B2/CYP11B1 in the other allele. Hormone Research, 63, 284293.
  • LaBuda, M., Gottesman, I., & Pauls, D. (1993). Usefulness of twin studies for exploring the etiology of childhood and adolescent psychiatric disorders. American Journal of Medical Genetics, 48, 4759.
  • Lawrence, E.J., Shaw, P., Baker, D., Baron-Cohen, S., & David, A.S. (2004). Measuring empathy—reliability and validity of the empathy quotient. Psychological Medicine, 34, 911919.
  • Lee, M., Chen, K., Shih, J., & Hiroi, N. (2004). MAO-B knockout mice exhibit deficient habituation of locomotor activity but normal nicotine intake. Genes, Brain and Behavior, 3, 216227.
  • Losh, M., & Piven, J. (2007). Social-cognition and the broad autism phenotype: identifying genetically meaningful phenotypes. Journal of Child Psychology and Psychiatry, 48, 105112.
  • Lujan, R., Shigemoto, R., & Lopez-Bendito, G. (2005). Glutamate and GABA signalling in the developing brain. Neuroscience, 130, 567580.
  • Lutchmaya, S., Baron-Cohen, S., Raggatt, P., & Manning, J.T. (2004). Maternal 2nd to 4th digit ratios and foetal testosterone. Early Human Development, 77, 2328.
  • Maltepe, E., Keith, B., Arsham, A., Brorson, J., & Simon, M. (2000). The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia. Biochemical and Biophysical Research Communications, 273, 231238.
  • Michaud, J., DeRossi, C., May, N., Holdener, B., & Fan, C. (2000). ARNT2 acts as the dimerization partner of SIM1 for the development of the hypothalamus. Mechanisms of Development, 90, 253261.
  • Moran, M.D. (2003). Arguments for rejecting the sequential Bonferroni in ecological studies. Oikos, 100, 403405.
  • Muscarella, L., Guarnieri, V., Sacco, R., Militerni, R., Bravaccio, C., et al. (2007). HOXA1 gene variants influence head growth rates in humans. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144B, 388390.
  • Purcell, S., Neale, B., Todd-Brown, K., Thomas, L., Ferreira, M.A.R., et al. (2007). PLINK: a toolset for whole-genome association and population-based linkage analysis. American Journal of Human Genetics, 81, 559575.
  • Robichaud, M., & Debonnel, G. (2005). Oestrogen and testosterone modulate the firing activity of dorsal raphe nucleus serotonergic neurones in both male and female rats. Journal of Neuroendocrinology, 17, 179185.
  • Sakamoto, H., Mezaki, Y., Shikimi, H., Ukena, K., & Tsutsui, K. (2003). Dendritic growth and spine formation in response to estrogen in the developing Purkinje cell. Endocrinology, 144, 44664477.
  • Sofroniew, M., Howe, C., & Mobley, W. (2001). Nerve growth factor signaling, neuroprotection, and neural repair. Annual Review of Neuroscience, 24, 12171281.
  • Sohrabji, F., Miranda, R., & Toran-Allenrand, C.D. (1994). Estrogen differentially regulates estrogen and nerve growth factor receptor mRNAs in adult sensory neuron. Journal of Neuroscience, 14, 459471.
  • Sung, Y., Dawson, G., Munson, J., Estes, A., Schellenberg, G., & Wijsman, E. (2005). Genetic investigation of quantitative traits related to autism: use of multivariate polygenic models with ascertainment adjustment. The American Journal of Human Genetics, 76, 6881.
  • Wakabayashi, A., Baron-Cohen, S., & Wheelwright, S. (2006). Are autistic traits an independent personality dimension? A study of the Autism Spectrum Quotient (AQ) and the NEO-PI-R. Personality and Individual Differences, 41, 873883.
  • Wing, L. 1988. The autistic continuum. In: Wing, L., editor. Aspects of autism: biological research. London: Gaskell/Royal College of Psychiatrists.
  • Woodbury-Smith, M., Robinson, J., Wheelwright, S., & Baron-Cohen, S. (2005). Screening adults for Asperger syndrome using the AQ: a preliminary study of its diagnostic validity in clinical practice. Journal of Autism and Developmental Disorders, 35, 331335.
  • Wu, S., Jia, M., Ruan, Y., Liu, J., Guo, Y., et al. (2005). Positive association of the oxytocin receptor gene (OXTR) with autism in the Chinese Han population. Biological Psychiatry, 58, 7477.
  • Yan, J., Oliveira, G., Coutinho, A., Yang, C., Feng, J., et al. (2005). Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients. Molecular Psychiatry, 10, 329332.
  • Ylisaukko-oja, T., Nieminen-von Wendt, T., Kempas, E., Sarenius, S., Varilo, T., et al. (2004). Genome-wide scan for loci of Asperger syndrome. Mol Psychiatry, 9, 161168.
  • Zahn-Waxler, C., Robinson, J.L., & Emde, R.N. (1992). The development of empathy in twins. Developmental Psychology, 28, 10381047.