Original Paper

The plasma pharmacokinetics and cerebral spinal fluid penetration of intravenous topiramate in newborn pigs†

  1. Jeffrey L. Galinkin1,2,‡,
  2. C. Dean Kurth1,§,
  3. Heng Shi2,§,
  4. Margaret A. Priestley1,
  5. Andreas W. Loepke1,§,
  6. Peter C. Adamson2,*

Article first published online: 7 JUL 2004

DOI: 10.1002/bdd.408

Issue

Biopharmaceutics & Drug Disposition

Biopharmaceutics & Drug Disposition

Volume 25, Issue 6, pages 265–271, September 2004

Additional Information

How to Cite

Galinkin, J. L., Kurth, C. D., Shi, H., Priestley, M. A., Loepke, A. W. and Adamson, P. C. (2004), The plasma pharmacokinetics and cerebral spinal fluid penetration of intravenous topiramate in newborn pigs. Biopharm. Drug Dispos., 25: 265–271. doi: 10.1002/bdd.408

Author Information

  1. 1

    Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, USA

  2. 2

    Division of Clinical Pharmacology and Therapeutics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, USA

  1. ‡

    Department of Anesthesia and Pediatrics, Cincinnati Children's Hospital, University of Cincinnati School of Medicine, Cincinnati, OH, USA

  2. §

    The Children's Hospital, Department of Anesthesia, University of Colorado Health Science Center, Denver, CO, USA

*The Children's Hospital of Philadelphia, 3615 Civic Center Blvd., ARC 916, Philadelphia, PA 19104-4399, USA

  1. †

    This work was presented at the meetings of the International Society for Anaesthetic Pharmacologists at Orlando, FL (October 11, 2002) and the American Society for Clinical Pharmacology and Therapeutics (April 9, 2003).

Publication History

  1. Issue published online: 7 JUL 2004
  2. Article first published online: 7 JUL 2004
  3. Manuscript Accepted: 8 APR 2004
  4. Manuscript Revised: 7 APR 2004
  5. Manuscript Received: 20 JAN 2004

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