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Sibutramine use in pregnancy: Report of two cases

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Abstract

Background

Sibutramine is a drug used for the medical treatment of obesity. No data are available on sibutramine use in pregnancy. We report the fetal outcomes of two pregnant women exposed to sibutramine.

Cases

The first woman was exposed to 10 mg/day of sibutramine during gestational weeks 4–6. The second woman was exposed to 10 mg/day of sibutramine during gestational weeks 5–8. At weeks 37 and 39, they delivered healthy infants.

CONCLUSIONS

To our knowledge, this is the first report of sibutramine exposure in pregnancy. These cases may contribute to the knowledge about sibutramine use during pregnancy. Birth Defects Research (Part A), 2004. © 2004 Wiley-Liss, Inc.

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