The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
Prepregnancy obesity: A complex risk factor for selected birth defects†
Article first published online: 1 JUN 2010
Copyright © 2010 Wiley-Liss, Inc.
Birth Defects Research Part A: Clinical and Molecular Teratology
Special Issue: 50th Anniversary of the Teratology Society
Volume 88, Issue 10, pages 804–810, October 2010
How to Cite
Carmichael, S. L., Rasmussen, S. A. and Shaw, G. M. (2010), Prepregnancy obesity: A complex risk factor for selected birth defects. Birth Defects Research Part A: Clinical and Molecular Teratology, 88: 804–810. doi: 10.1002/bdra.20679
- Issue published online: 1 JUN 2010
- Article first published online: 1 JUN 2010
- Manuscript Accepted: 11 APR 2010
- Manuscript Revised: 6 APR 2010
- Manuscript Received: 10 MAR 2010
- birth defects;
Obesity is associated with increased risk of many adverse health conditions. During pregnancy, obesity presents particularly important challenges for both mother and baby. Over the last 20 years, studies have emerged indicating an association between prepregnancy weight and risks of birth defects. However, few studies have examined the mechanisms through which this association occurs. Understanding the underlying mechanisms may provide clues to public health strategies for the prevention of birth defects associated with maternal obesity. This article briefly reviews existing literature on the association between maternal obesity and birth defects, discusses potential underlying mechanisms, and suggests research needed to improve our understanding of this important association. Birth Defects Research (Part A) 2010. © 2010 Wiley-Liss, Inc.