The lack of histological changes of CDMA cellular phone-based radio frequency on rat testis
Article first published online: 6 JUL 2010
Copyright © 2010 Wiley-Liss, Inc.
Volume 31, Issue 7, pages 528–534, October 2010
How to Cite
Lee, H.-J., Pack, J.-K., Kim, T.-H., Kim, N., Choi, S.-Y., Lee, J.-S., Kim, S.-H. and Lee, Y.-S. (2010), The lack of histological changes of CDMA cellular phone-based radio frequency on rat testis. Bioelectromagnetics, 31: 528–534. doi: 10.1002/bem.20589
- Issue published online: 6 SEP 2010
- Article first published online: 6 JUL 2010
- Manuscript Accepted: 21 APR 2010
- Manuscript Received: 16 MAR 2009
- Korea Communications Commission (KCC)
- RF exposure;
- 848.5 MHz;
- rat spermatogenesis
We examined the histological changes by radiofrequency (RF) fields on rat testis, specifically with respect to sensitive processes such as spermatogenesis. Male rats were exposed to 848.5 MHz RF for 12 weeks. The RF exposure schedule consisted of two 45-min RF exposure periods, separated by a 15-min interval. The whole-body average specific absorption rate (SAR) of RF was 2.0 W/kg. We then investigated correlates of testicular function such as sperm counts in the cauda epididymis, malondialdehyde concentrations in the testes and epididymis, frequency of spermatogenesis stages, germ cell counts, and appearance of apoptotic cells in the testes. We also performed p53, bcl-2, caspase 3, p21, and PARP immunoblotting of the testes in sham- and RF-exposed animals. Based on these results, we concluded that subchronic exposure to 848.5 MHz with 2.0 W/kg SAR RF did not have any observable adverse effects on rat spermatogenesis. Bioelectromagnetics 31:528–534, 2010. © 2010 Wiley-Liss, Inc.