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Family of the green fluorescent protein: Journey to the end of the rainbow

  1. Mikhail V. Matz1,*,
  2. Konstantin A. Lukyanov2,
  3. Sergey A. Lukyanov2

Article first published online: 25 SEP 2002

DOI: 10.1002/bies.10154

Issue

BioEssays

BioEssays

Volume 24, Issue 10, pages 953–959, October 2002

Additional Information

How to Cite

Matz, M. V., Lukyanov, K. A. and Lukyanov, S. A. (2002), Family of the green fluorescent protein: Journey to the end of the rainbow. BioEssays, 24: 953–959. doi: 10.1002/bies.10154

Author Information

  1. 1

    Whitney Laboratory, University of Florida

  2. 2

    Evrogen JSC, Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia

*Whitney Laboratory, University of Florida, St Augustine.

Publication History

  1. Issue published online: 25 SEP 2002
  2. Article first published online: 25 SEP 2002

Funded by

  • NIH. Grant Number: 1R01 GM/EB66243 to M.V.M
  • Russian Foundation for Fundamental Research. Grant Number: 01-04-49037 to S.A.L

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Abstract

Members of the family of the Green Fluorescent Protein (GFP) are the only known type of natural pigments that are essentially encoded by a single gene, since both the substrate for pigment biosynthesis and the necessary catalytic moieties are provided within a single polypeptide chain. In sharp contrast to the state of knowledge just three years ago when GFP was the only known protein of its kind, a whole family of related proteins, exhibiting striking diversity of features have now been identified. This provides new possibilities for a variety of studies ranging from applied biotechnology to evolutionary ecology. BioEssays 24:953–959, 2002. © 2002 Wiley Periodicals, Inc.

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