Prospects & Overviews
Mitochondrial manoeuvres: Latest insights and hypotheses on mitochondrial partitioning during mitosis in Saccharomyces cerevisiae
Article first published online: 30 SEP 2010
Copyright © 2010 WILEY Periodicals, Inc.
Volume 32, Issue 12, pages 1040–1049, December 2010
How to Cite
Peraza-Reyes, L., Crider, D. G. and Pon, L. A. (2010), Mitochondrial manoeuvres: Latest insights and hypotheses on mitochondrial partitioning during mitosis in Saccharomyces cerevisiae. Bioessays, 32: 1040–1049. doi: 10.1002/bies.201000083
- Issue published online: 18 NOV 2010
- Article first published online: 30 SEP 2010
- Manuscript Accepted: 24 AUG 2010
- Manuscript Revised: 19 AUG 2010
- Manuscript Received: 30 JUN 2010
- cell division;
- organelle inheritance;
- Saccharomyces cerevisiae
Movement and positional control of mitochondria and other organelles are coordinated with cell cycle progression in the budding yeast, Saccharomyces cerevisiae. Recent studies have revealed a checkpoint that inhibits cytokinesis when there are severe defects in mitochondrial inheritance. An established checkpoint signaling pathway, the mitotic exit network (MEN), participates in this process. Here, we describe mitochondrial motility during inheritance in budding yeast, emerging evidence for mitochondrial quality control during inheritance, and organelle inheritance checkpoints for mitochondria and other organelles.