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Keywords:

  • cancer;
  • cellular interactions;
  • differentiation therapy;
  • stabilization model of cell differentiation;
  • stochastic gene expression
Thumbnail image of graphical abstract

Current differentiation therapies for cancer may not be effective because it might not be enough to only use molecules targeting chromatin remodelers. It may also be necessary to stabilize the re-expressed genes to convert malignant cells into benign ones.