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Insights & Perspectives
Instructive reconstruction: A new role for apoptosis in pattern formation
Instructive apoptotic patterning establishes de novo tissue generation via the apoptosis linked production of morphogenic signals
Article first published online: 10 APR 2012
DOI: 10.1002/bies.201200018
Copyright © 2012 WILEY Periodicals, Inc.
Additional Information
How to Cite
Duffy, D. J. (2012), Instructive reconstruction: A new role for apoptosis in pattern formation. Bioessays, 34: 561–564. doi: 10.1002/bies.201200018
Publication History
- Issue published online: 14 JUN 2012
- Article first published online: 10 APR 2012
Funded by
- Science Foundation Ireland (SFI). Grant Number: 06/CE/B1129
- Abstract
- Article
- References
- Cited By
Keywords:
- Cnidaria;
- development;
- heat shock protein;
- metamorphosis;
- regeneration;
- Wnt
Apoptosis is not only involved in patterning by removal of tissue (destructive apoptotic patterning), but it can also function in signalling the site of de novo tissue generation via morphogenic signals (instructive apoptotic patterning).