Insights & Perspectives
Does human evolution in different latitudes influence susceptibility to obesity via the circadian pacemaker?
Migration and survival of the fittest in the modern age of lifestyle-induced circadian desynchrony
Version of Record online: 30 AUG 2012
Copyright © 2012 WILEY Periodicals, Inc.
Volume 34, Issue 11, pages 921–924, November 2012
How to Cite
Wyse, C. A. (2012), Does human evolution in different latitudes influence susceptibility to obesity via the circadian pacemaker?. Bioessays, 34: 921–924. doi: 10.1002/bies.201200067
- Issue online: 12 OCT 2012
- Version of Record online: 30 AUG 2012
The variable photoperiods of Northern latitudes challenge the entrainment capacity of the circadian pacemaker, which evolved under constant photoperiods in Equatorial regions. Entrainment to the erratic photoperiods facilitated by artificial light presents an additional challenge. Metabolic dysfunction and obesity are potential consequences of such desynchronization of circadian and environmental rhythms.