Prospects & Overviews
Cooperation and the evolutionary ecology of bacterial virulence: The Bacillus cereus group as a novel study system
Article first published online: 23 MAY 2013
© 2013 WILEY Periodicals, Inc.
Volume 35, Issue 8, pages 706–716, August 2013
How to Cite
Raymond, B. and Bonsall, M. B. (2013), Cooperation and the evolutionary ecology of bacterial virulence: The Bacillus cereus group as a novel study system. Bioessays, 35: 706–716. doi: 10.1002/bies.201300028
- Issue published online: 15 JUL 2013
- Article first published online: 23 MAY 2013
- NERC, BBSRC and the Royal Society
- host range;
- microbial ecology;
- social evolution;
How significant is social evolution theory for the maintenance of virulence in natural populations? We assume that secreted, distantly acting virulence factors are highly likely to be cooperative public goods. Using this assumption, we discuss and critically assess the potential importance of social interactions for understanding the evolution, diversity and distribution of virulence in the Bacillus cereus group, a novel study system for microbial social biology. We conclude that dynamic equilibria in Cry toxin production, as well as strong spatial structure and population bottlenecks in hosts are the main ecological factors maintaining the cooperative secretion of virulence factors and argue that collective action has contributed to the evolution of narrow host range. Non-linearities in the benefits associated with public goods, as well as the lack of private secretion systems in the Firmicutes may also explain the prevalence and importance of distantly acting virulence factors in B. cereus and its relatives.