From the margins of the genome: mobile elements shape primate evolution

Authors

  • Dale J. Hedges,

    1. Department of Biological Sciences, Biological Computation and Visualization Center, Center for BioModular Multi-scale Systems, Louisiana State University, LA
    Search for more papers by this author
  • Mark A. Batzer

    Corresponding author
    1. Department of Biological Sciences, Biological Computation and Visualization Center, Center for BioModular Multi-scale Systems, Louisiana State University, LA
    • Department of Biological Sciences, Biological Computation and Visualization Center, Center for BioModular Multi-scale Systems, Louisiana State University, 202 Life Sciences Building, Baton Rouge, LA 70803.
    Search for more papers by this author

Abstract

As is the case with mammals in general, primate genomes are inundated with repetitive sequence. Although much of this repetitive content consists of “molecular fossils” inherited from early mammalian ancestors, a significant portion of this material comprises active mobile element lineages. Despite indications that these elements played a major role in shaping the architecture of the genome, there remain many unanswered questions surrounding the nature of the host-element relationship. Here we review advances in our understanding of the host–mobile element dynamic and its overall impact on primate evolution. BioEssays 27:785–794, 2005. © 2005 Wiley Periodicals, Inc.

Ancillary