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What the papers say
Paralogs and mutational robustness linked through transcriptional reprogramming†
Article first published online: 17 AUG 2005
DOI: 10.1002/bies.20296
Copyright © 2005 Wiley Periodicals, Inc.
Additional Information
How to Cite
Koonin, E. V. (2005), Paralogs and mutational robustness linked through transcriptional reprogramming. Bioessays, 27: 865–868. doi: 10.1002/bies.20296
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Publication History
- Issue published online: 17 AUG 2005
- Article first published online: 17 AUG 2005
- Abstract
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Abstract
A recent analysis of genome-wide expression patterns and regulatory motif content of paralogous yeast genes1 strongly suggests that mutational robustness (backup) between paralogous genes is achieved via transcriptional reprogramming of one paralog to compensate for the loss or silencing of the other. BioEssays 27:865–868, 2005. Published 2005 Wiley Periodicals, Inc.