BioEssays

Cover image for Vol. 33 Issue 2

February 2011

Volume 33, Issue 2

Pages 85–147

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents and highlights of this issue
    5. Insights & Perspectives
    6. Prospects & Overviews
    7. Biotec Visions
    8. Next Issue
    1. BioEssays 2/2011

      Article first published online: 17 JAN 2011 | DOI: 10.1002/bies.201190002

      Cover Photograph: Mitochondrial oxygen radicals resulting from competition for CoQ by complex I and other respiratory complexes, illustrate a kinetic theory of oxygen radical formation in eukaryotes as proposed by Speijer on pages 88–94 of this issue. The theory is used to explain the eukaryotic invention of peroxisomes, stating their primary function to be reduction of FADH2 amounts, generated as very long chain fatty acids are oxidized. It also sheds light on the reason for increased radical formation during the breakdown of fatty acids in general, and why neurons, which can not be easily replaced, thus have to forego this form of highly efficient energy generation. Last but not least, it could also explain why unsaturated fatty acids seem to be much healthier than their saturated counterparts, as they produce less FADH2 during breakdown. Mitochondrial oxygen radical formation could have been shaping evolution from the beginning of the eukaryotic lineage, and seems to be still doing so in complex vertebrates like ourselves. Image conceived and developed by Nick Dekker and Dave Speijer.

  2. Editorial

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents and highlights of this issue
    5. Insights & Perspectives
    6. Prospects & Overviews
    7. Biotec Visions
    8. Next Issue
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  3. Contents and highlights of this issue

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents and highlights of this issue
    5. Insights & Perspectives
    6. Prospects & Overviews
    7. Biotec Visions
    8. Next Issue
    1. You have free access to this content
      BioEssays 2/2011 (pages 86–87)

      Article first published online: 17 JAN 2011 | DOI: 10.1002/bies.201190001

  4. Insights & Perspectives

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents and highlights of this issue
    5. Insights & Perspectives
    6. Prospects & Overviews
    7. Biotec Visions
    8. Next Issue
    1. Hypotheses

    2. Ideas & Speculations

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    3. Commentary

  5. Prospects & Overviews

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents and highlights of this issue
    5. Insights & Perspectives
    6. Prospects & Overviews
    7. Biotec Visions
    8. Next Issue
    1. Recently in press

    2. Review essays

    3. Problems & Paradigms

  6. Biotec Visions

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents and highlights of this issue
    5. Insights & Perspectives
    6. Prospects & Overviews
    7. Biotec Visions
    8. Next Issue
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      Biotec Visions: BioEssays 2/2011

      Article first published online: 17 JAN 2011 | DOI: 10.1002/bies.201190003

  7. Next Issue

    1. Top of page
    2. Cover Picture
    3. Editorial
    4. Contents and highlights of this issue
    5. Insights & Perspectives
    6. Prospects & Overviews
    7. Biotec Visions
    8. Next Issue
    1. You have free access to this content
      BioEssays – Next Issue

      Article first published online: 17 JAN 2011 | DOI: 10.1002/bies.201190004

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