Wenwen Fang and Laura F. Landweber
RNA's role in genome rearrangement. Ciliated protists, such as Oxytricha, shown, have two types of nuclei that differentiate from each other. Development in these microbial eukaryotes provides a paragon for studies of genome remodeling, with extensive use of non-coding RNAs. On pages 84–87 of this issue, Wenwen Fang and Laura Landweber discuss how RNA-guided processes of genome rearrangement or repair could influence other eukaryotes. Cover by Wenyi Fang. SEM images courtesy of Robert Hammersmith.