Improved Exact Confidence Intervals for the Odds Ratio in Two Independent Binomial Samples



For two independent binomial samples, the usual exact confidence interval for the odds ratio based on the conditional approach can be very conservative. Recently, Agresti and Min (2002) showed that the unconditional intervals are preferable to conditional intervals with small sample sizes. We use the unconditional approach to obtain a modified interval, which has shorter length, and its coverage probability is closer to and at least the nominal confidence coefficient. (© 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)