An in vitro model of glucose and lipid metabolism in a multicompartmental bioreactor (pages 117–126)
Bruna Vinci, Ellen Murphy, Elisabetta Iori, Francesco Meduri, Silvia Fattori, Maria Cristina Marescotti, Maura Castagna, Angelo Avogaro and Professor Arti Ahluwalia
Version of Record online: 7 OCT 2011 | DOI: 10.1002/biot.201100177
It is accepted that current in-vitro cell culture systems are poorly representative of human or animal physiology. In this article, the authors attempt to improve the current 2D culture systems with a modular multicompartmental bioreactor (MCmB) system, which provides an in vitro model of glucose and lipid metabolism that is more reflective of the actual situation in vivo.