Vibrational analysis of peptides, polypeptides, and proteins. II. β-Poly(L-alanine) and β-poly(L-alanylglycine)
Version of Record online: 1 FEB 2004
Copyright © 1976 John Wiley & Sons, Inc.
Volume 15, Issue 12, pages 2465–2483, December 1976
How to Cite
Moore, W. H. and Krimm, S. (1976), Vibrational analysis of peptides, polypeptides, and proteins. II. β-Poly(L-alanine) and β-poly(L-alanylglycine). Biopolymers, 15: 2465–2483. doi: 10.1002/bip.1976.360151211
- Issue online: 1 FEB 2004
- Version of Record online: 1 FEB 2004
- Manuscript Accepted: 12 JUL 1976
- Manuscript Received: 10 MAY 1976
The normal vibration frequencies of poly(L-alanine) and poly(L-alanylglycine) in the antiparallel chain-pleated sheet structure have been calculated, using the force field for polyglycine I from the previous paper (Biopolymers15, 2439–2464) plus additional force constants for the methyl group. The agreement with observed ir and Raman bands is very good. This substantiates the excellent transferability of the force field, since polyglycine I was shown to have a rippled-sheet structure. The amide I and amide II mode splittings are very well accounted for by transition dipole coupling, showing that subtle structural differences are sensitively manifested through this mechanism.