4-Chloroprolines: Synthesis, conformational analysis, and effect on the collagen triple helix†

  1. Matthew D. Shoulders1,
  2. Ilia A. Guzei1,
  3. Ronald T. Raines1,2,*

Article first published online: 15 OCT 2007

DOI: 10.1002/bip.20864

Issue

Biopolymers

Biopolymers

Special Issue: This issue is dedicated to the memory of Elkan R. Blout, a founding editor of Biopolymers

Volume 89, Issue 5, pages 443–454, May 2008

Additional Information

How to Cite

Shoulders, M. D., Guzei, I. A. and Raines, R. T. (2008), 4-Chloroprolines: Synthesis, conformational analysis, and effect on the collagen triple helix. Biopolymers, 89: 443–454. doi: 10.1002/bip.20864

Author Information

  1. 1

    Department of Chemistry, University of Wisconsin–Madison, 1101 University Avenue, Madison, WI 53706-1322

  2. 2

    Department of Biochemistry, University of Wisconsin–Madison, 433 Babcock Drive, Madison, WI 53706-1544

*Department of Chemistry, University of Wisconsin–Madison, 1101 University Avenue, Madison, WI 53706-1322

  1. †

    This work is dedicated to the memory of Elkan R. Blout, a pioneer of spectroscopic methods for the structural characterization of proteins and peptides. Professor Blout was among the first to employ collagen-mimetic peptides for the study of native collagen structure, an approach that continues to provide important insights.

Publication History

  1. Issue published online: 28 FEB 2008
  2. Article first published online: 15 OCT 2007
  3. Manuscript Accepted: 5 OCT 2007
  4. Manuscript Revised: 2 OCT 2007
  5. Manuscript Received: 15 AUG 2007

Funded by

  • NIH. Grant Numbers: AR44276, RR13790, P41 RR02301
  • NSF. Grant Number: BIR-9512577

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