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Additional Supporting Information may be found in the online version of this article.

FilenameFormatSizeDescription
bip22229-sup-0001-suppinfo.docx53KSupplementary Table 1. In vitro tests of cyclotides on the different species/strains of schistosomes. Worms were incubated in RPMI-1640 medium supplemented with 20% (v/v) foetal bovine serum, 100 U/ml penicillin and 100 μg/ml streptomycin at 37 ˚C with an atmosphere of 5% CO2 at different drugs concentrations from stock solutions in acetonitrile (final solvent concentration 2%).
bip22229-sup-0002-suppinfo.docx74KSupplementary Table 2. Cumulative percentage of schistosome mortality over 24 hours for different trials.
bip22229-sup-0003-suppinfo.tif839KSupplementary Figure 1
bip22229-sup-0004-suppinfo.tif848KSupplementary Figure 2

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