Revealing structural views of biology

Authors

  • David S. Goodsell,

    1. RCSB Protein Data Bank and Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA
    Search for more papers by this author
  • Stephen K. Burley,

    1. RCSB Protein Data Bank, Department of Chemistry and Chemical Biology, and Center for Integrative Proteomics Research, Rutgers, The State University of New Jersey, Piscataway, NJ
    Search for more papers by this author
  • Helen M. Berman

    Corresponding author
    1. RCSB Protein Data Bank, Department of Chemistry and Chemical Biology, and Center for Integrative Proteomics Research, Rutgers, The State University of New Jersey, Piscataway, NJ
    Search for more papers by this author

  • This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com

ABSTRACT

The first protein structures were determined in the 1950s. In the decades that followed, development of new methods for sample preparation, crystallization, data collection, and structure analysis yielded tens of thousands of biomolecular structures. This short review highlights some of the major technical advances exemplified with selected structures. © 2013 The Authors. Published by Wiley Periodicals, Inc. Biopolymers 99: 817–824, 2013.

Ancillary