Communication to the Editor

Engineering motility as a phenotypic response to LuxI/R-dependent quorum sensing in Escherichia coli

  1. Lucien E. Weiss1,2,
  2. Jonathan P. Badalamenti1,
  3. Lane J. Weaver1,2,
  4. Anthony R. Tascone1,3,
  5. Paul S. Weiss1,2,4,
  6. Tom L. Richard1,5,
  7. Patrick C. Cirino1,3,*

Article first published online: 7 MAR 2008

DOI: 10.1002/bit.21862

Issue

Biotechnology and Bioengineering

Biotechnology and Bioengineering

Volume 100, Issue 6, pages 1251–1255, 15 August 2008

Additional Information

How to Cite

Weiss, L. E., Badalamenti, J. P., Weaver, L. J., Tascone, A. R., Weiss, P. S., Richard, T. L. and Cirino, P. C. (2008), Engineering motility as a phenotypic response to LuxI/R-dependent quorum sensing in Escherichia coli. Biotechnol. Bioeng., 100: 1251–1255. doi: 10.1002/bit.21862

Author Information

  1. 1

    The Pennsylvania State University iGEM Group, The Pennsylvania State University, University Park, Pennsylvania 16802; telephone: 814-865-5790; fax: 814-865-7846

  2. 2

    Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania

  3. 3

    Department of Chemical Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802

  4. 4

    Department of Physics, The Pennsylvania State University, University Park, Pennsylvania

  5. 5

    Department of Agricultural and Biological Engineering, The Pennsylvania State University, University Park, Pennsylvania

*The Pennsylvania State University iGEM Group, The Pennsylvania State University, University Park, Pennsylvania 16802; telephone: 814-865-5790; fax: 814-865-7846.

Publication History

  1. Issue published online: 13 JUN 2008
  2. Article first published online: 7 MAR 2008
  3. Accepted manuscript online: 7 MAR 2008 12:00AM EST
  4. Manuscript Accepted: 14 FEB 2008
  5. Manuscript Revised: 8 FEB 2008
  6. Manuscript Received: 10 JAN 2008

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Keywords:

  • synthetic biology;
  • quorum sensing;
  • motility;
  • motB;
  • Escherichia coli;
  • LuxI

Abstract

The repertoire of functional outputs interfaced with the LuxI/LuxR quorum sensing system in engineered Escherichia coli has been expanded to include motility via inducible expression of motB. Appropriate choice of ribosome binding site controlling MotB translation was crucial to achieving control over motility. Biotechnol. Biotechnol. Bioeng. 2008;100: 1251–1255. © 2008 Wiley Periodicals, Inc.

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