J.H.P. and B.G.C. designed and performed the experiments, and analyzed the data. W.G.L. fabricated agarose channels and analyzed the data. J.S.K. conceived the methodology for creating micropores and analyzed confocal images. M.B. measured the porosity and characterized mechanical strength. J.S. characterized diffusion coefficient and profiles. S.H.L. synthesized biomaterials, characterized porosity, and analyzed the data. C.H. performed cell experiments and analyzed the data. G.D. created and characterized pores within agarose gels using sucrose mixtures. U.D. helped in analysis of the data. A.K. supervised the work and conceived of the idea. All authors read and wrote the paper.
Article first published online: 20 JAN 2010
Copyright © 2010 Wiley Periodicals, Inc.
Biotechnology and Bioengineering
Volume 106, Issue 1, pages 138–148, 1 May 2010
How to Cite
Park, J. H., Chung, B. G., Lee, W. G., Kim, J., Brigham, M. D., Shim, J., Lee, S., Hwang, C. M., Durmus, N. G., Demirci, U. and Khademhosseini, A. (2010), Microporous cell-laden hydrogels for engineered tissue constructs. Biotechnol. Bioeng., 106: 138–148. doi: 10.1002/bit.22667
Jae Hong Park and Bong Geun Chung equally contributed to this work.
- Issue published online: 19 MAR 2010
- Article first published online: 20 JAN 2010
- Accepted manuscript online: 20 JAN 2010 12:00AM EST
- Manuscript Accepted: 30 DEC 2009
- Manuscript Revised: 17 DEC 2009
- Manuscript Received: 24 AUG 2009
- The National Institutes of Health. Grant Numbers: DE019024, HL092836, EB007249
- US Army Core of Engineers
- The Charles Stark Draper Laboratory
- Korea Research Foundation Grant (MOEHRD). Grant Number: KRF-2007-357-D00101
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