Article

High-End pH-controlled delivery of glucose effectively suppresses lactate accumulation in CHO Fed-batch cultures

  1. Matthew Gagnon1,
  2. Gregory Hiller1,*,
  3. Yen-Tung Luan1,
  4. Amy Kittredge2,
  5. Jordy DeFelice1,
  6. Denis Drapeau1

Article first published online: 24 FEB 2011

DOI: 10.1002/bit.23072

Issue

Biotechnology and Bioengineering

Biotechnology and Bioengineering

Volume 108, Issue 6, pages 1328–1337, June 2011

Additional Information

How to Cite

Gagnon, M., Hiller, G., Luan, Y.-T., Kittredge, A., DeFelice, J. and Drapeau, D. (2011), High-End pH-controlled delivery of glucose effectively suppresses lactate accumulation in CHO Fed-batch cultures. Biotechnol. Bioeng., 108: 1328–1337. doi: 10.1002/bit.23072

Author Information

  1. 1

    Pfizer, Inc., 1 Burtt Road, Andover, Massachusetts; telephone: 978-247-3173; fax: 978-247-2602

  2. 2

    Millipore, Inc., Billerica, Massachusetts

*Pfizer, Inc., 1 Burtt Road, Andover, Massachusetts; telephone: 978-247-3173; fax: 978-247-2602.

Publication History

  1. Issue published online: 12 APR 2011
  2. Article first published online: 24 FEB 2011
  3. Accepted manuscript online: 15 FEB 2011 12:00AM EST
  4. Manuscript Accepted: 18 JAN 2011
  5. Manuscript Revised: 23 DEC 2010
  6. Manuscript Received: 7 OCT 2010

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