Author Contributions: K.Y.W. and Y.Y.C. designed research, constructed and characterized ribozyme-based devices in HEK cells, and wrote the paper; K.Y.W. characterized devices in HeLa and U2OS cells and performed quantitative comparisons against yeast data; Y.Y.C. generated HEK cell lines stably expressing ribozyme devices; C.D.S. designed research and wrote the paper.
A yeast-based rapid prototype platform for gene control elements in mammalian cells†
Article first published online: 17 JAN 2013
Copyright © 2012 Wiley Periodicals, Inc.
Biotechnology and Bioengineering
Volume 110, Issue 4, pages 1201–1210, April 2013
How to Cite
Wei, K. Y., Chen, Y. Y. and Smolke, C. D. (2013), A yeast-based rapid prototype platform for gene control elements in mammalian cells. Biotechnol. Bioeng., 110: 1201–1210. doi: 10.1002/bit.24792
- Issue published online: 22 FEB 2013
- Article first published online: 17 JAN 2013
- Accepted manuscript online: 26 NOV 2012 09:09AM EST
- Manuscript Accepted: 12 NOV 2012
- Manuscript Revised: 23 OCT 2012
- Manuscript Received: 8 AUG 2012
- National Institutes of Health. Grant Number: RC1GM091298
- Defense Advanced Research Projects Agency. Grant Number: HR0011-11-2-0002
- National Science Foundation
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