SEARCH

SEARCH BY CITATION

Additional supporting information may be found in the online version of this article at the publisher's web-site.

FilenameFormatSizeDescription
bit24941-sm-0001-SupData.docx950KSupplimentary Data
bit24941-sm-0002-SupFig-S1.docx1662KFigure S1. Concentrations of acetate, pyruvate, 2-ketoglutarate, and NH+ in Medium I and Medium II. The values shown represent the means of five independent experiments and the error bars represent standard deviations of five values.
bit24941-sm-0003-SupFig-S2.doc394KFigure S2. The effects of leucine and threonine feeding strategies on FK506 biosynthesis. The strategies contain different concentrations (g/L) of leucine and threonine at various feeding time. Dash line represented the initial titer (251 mg/L). The values shown represent the means of five independent experiments and the error bars represent standard deviations of five values.
bit24941-sm-0004-SupTab-S1.doc115KTable S1. List of identified and putatively annotated metabolites measured by GC–MS, LC–MS/MS and HPLC–ESI–MS/MS.
bit24941-sm-0005-SupTab-S2.docx19KTable S2. The key metabolites responsible for the discrimination between Medium I and Medium II determined by PCA.

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.