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Figure S1. Fluorescence images of HeLa cells delivered with different ratio of Alexa-labeled H-MA-ET to Qdot.

Figure S2. Temporal capture of QD-H-MA-ET processing.

Figure S3. Confirmation of HIV-1 Pr specificity using a non-specific probe H-WNV-ET sensitive to the West Nile Virus protease.

Figure S4. Verification of mutant protease action on H-MA-ET and QD conjugate with time in comparison with the wild type.

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