A thermodynamically based correlation for maintenance gibbs energy requirements in aerobic and anaerobic chemotrophic growth
Article first published online: 19 FEB 2004
Copyright © 1993 John Wiley & Sons, Inc.
Biotechnology and Bioengineering
Volume 42, Issue 4, pages 509–519, 5 August 1993
How to Cite
Tijhuis, L., Van Loosdrecht, M. C. M. and Heijnen, J. J. (1993), A thermodynamically based correlation for maintenance gibbs energy requirements in aerobic and anaerobic chemotrophic growth. Biotechnol. Bioeng., 42: 509–519. doi: 10.1002/bit.260420415
- Issue published online: 19 FEB 2004
- Article first published online: 19 FEB 2004
- Manuscript Accepted: 8 MAR 1993
- Manuscript Received: 11 NOV 1992
- Gibbs energy requirements;
- chemotrophic growth;
- anaerobic and aerobic
A thermodynamic framework has been provided for the description of maintenance requirements of microorganisms. The central parameter is the biomass specific Gibbs energy consumption for maintenance, mE (kJ/C-mol biomass · h). A large set of data has been used including (i) a large range of different organisms (bacteria, yeasts, plant cells), (ii) mixed cultures, (iii) heterotrophic and autotrophic growth, (iv) growth under aerobic and anaerobic conditions, and (v) a large temperature range (5–75°C). It appears that only the temperature has a major influence, with an energy of activation of 69 kJ/mol. Different electron donors or electron acceptors only show a very minor influence on mE. On the basis of the data set, temperature correlations of mE have been derived for aerobic and anaerobic growth. The generalized concept for maintenance Gibbs energy is used to establish a correlation which allows the estimation of the biomass yield on electron donor as a function of C-source, electron donor, electron acceptor, N source, growth rate, and temperature. The advantage of using the mE parameter over other maintenance-related parameters (like μe, mO2, mD, γDmD) is discussed. © 1993 John Wiley & Sons, Inc.