Skin tissue generation by laser cell printing (pages 1855–1863)
Lothar Koch, Andrea Deiwick, Sabrina Schlie, Stefanie Michael, Martin Gruene, Vincent Coger, Daniela Zychlinski, Axel Schambach, Kerstin Reimers, Peter M. Vogt and Boris Chichkov
Article first published online: 13 FEB 2012 | DOI: 10.1002/bit.24455
With the aim of engineering functional tissue, a laser-based cell printing technique is used to arrange living cells in 3D patterns as multicellular grafts analogous to native skin archetype. Cell functions and the tissue formation process are studied, e.g. by analyzing the formation of adherens and gap junctions, which are fundamental for tissue morphogenesis and cohesion.