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Biotechnology and Bioengineering

Cover image for Vol. 84 Issue 7

Special Issue: Systems Approaches to Biotechnology: Systems Biotechnology in the Making

30 December 2003

Volume 84, Issue 7

Pages 739–899

Issue edited by: Vassily Hatzimanikatis, Christos Ouzounis, John Quackenbush

  1. Regular Article

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      The quest for the mechanisms of life (pages 739–742)

      Maria I. Klapa and John Quackenbush

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10858

  2. Articles

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      Environmental conditions and transcriptional regulation in Escherichia coli: a physiological integrative approach (pages 743–749)

      Agustino Martínez-Antonio, Heladia Salgado, Socorro Gama-Castro, Rosa María Gutiérrez-Ríos, Verónica Jiménez-Jacinto and Julio Collado-Vides

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10846

  3. Article

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      Metabolic database systems for the analysis of genome-wide function (pages 750–755)

      Sophia Tsoka and Christos A. Ouzounis

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10881

  4. Regular Article

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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  5. Articles

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      The complexity of complexes in signal transduction (pages 783–794)

      William S. Hlavacek, James R. Faeder, Michael L. Blinov, Alan S. Perelson and Byron Goldstein

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10842

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      Maintaining data integrity in microarray data management (pages 795–800)

      G. R. Grant, E. Manduchi, A. Pizarro and C. J. Stoeckert Jr.

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10847

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      A perspective of metabolic engineering strategies: moving up the systems hierarchy (pages 815–821)

      Thomas Bulter, Jeffrey R. Bernstein and James C. Liao

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10845

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      Insights into the relation between mrna and protein expression patterns: ii. Experimental observations in Escherichia coli (pages 834–841)

      Pat S. Lee, Leah B. Shaw, Leila H. Choe, Amit Mehra, Vassily Hatzimanikatis and Kelvin H. Lee

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10841

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      Transcriptional analysis of product-concentration driven changes in cellular programs of recombinant Clostridium acetobutylicumstrains (pages 842–854)

      Seshu B. Tummala, Stefan G. Junne, Carlos J. Paredes and Eleftherios T. Papoutsakis

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10851

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      Exploring the overproduction of amino acids using the bilevel optimization framework OptKnock (pages 887–899)

      Priti Pharkya, Anthony P. Burgard and Costas D. Maranas

      Version of Record online: 30 DEC 2003 | DOI: 10.1002/bit.10857

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