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Biotechnology and Bioengineering

Cover image for Vol. 84 Issue 7

Special Issue: Systems Approaches to Biotechnology: Systems Biotechnology in the Making

30 December 2003

Volume 84, Issue 7

Pages 739–899

Issue edited by: Vassily Hatzimanikatis, Christos Ouzounis, John Quackenbush

  1. Regular Article

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      The quest for the mechanisms of life (pages 739–742)

      Maria I. Klapa and John Quackenbush

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10858

  2. Articles

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      Environmental conditions and transcriptional regulation in Escherichia coli: a physiological integrative approach (pages 743–749)

      Agustino Martínez-Antonio, Heladia Salgado, Socorro Gama-Castro, Rosa María Gutiérrez-Ríos, Verónica Jiménez-Jacinto and Julio Collado-Vides

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10846

  3. Article

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      Metabolic database systems for the analysis of genome-wide function (pages 750–755)

      Sophia Tsoka and Christos A. Ouzounis

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10881

  4. Regular Article

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      Exploiting evolutionary relationships for predicting protein structures (pages 756–762)

      Anna Tramontano and Veronica Morea

      Article first published online: 28 OCT 2003 | DOI: 10.1002/bit.10850

  5. Articles

    1. Top of page
    2. Regular Article
    3. Articles
    4. Article
    5. Regular Article
    6. Articles
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      The complexity of complexes in signal transduction (pages 783–794)

      William S. Hlavacek, James R. Faeder, Michael L. Blinov, Alan S. Perelson and Byron Goldstein

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10842

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      Maintaining data integrity in microarray data management (pages 795–800)

      G. R. Grant, E. Manduchi, A. Pizarro and C. J. Stoeckert Jr.

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10847

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      A perspective of metabolic engineering strategies: moving up the systems hierarchy (pages 815–821)

      Thomas Bulter, Jeffrey R. Bernstein and James C. Liao

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10845

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      Insights into the relation between mRNA and protein expression patterns: I. theoretical considerations (pages 822–833)

      Amit Mehra, Kelvin H. Lee and Vassily Hatzimanikatis

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10860

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      Insights into the relation between mrna and protein expression patterns: ii. Experimental observations in Escherichia coli (pages 834–841)

      Pat S. Lee, Leah B. Shaw, Leila H. Choe, Amit Mehra, Vassily Hatzimanikatis and Kelvin H. Lee

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10841

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      Transcriptional analysis of product-concentration driven changes in cellular programs of recombinant Clostridium acetobutylicumstrains (pages 842–854)

      Seshu B. Tummala, Stefan G. Junne, Carlos J. Paredes and Eleftherios T. Papoutsakis

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10851

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      Theoretical and computational studies of the glucose signaling pathways in yeast using global gene expression data (pages 864–886)

      Xiaoxia Lin, Christodoulos A. Floudas, Ying Wang and James R. Broach

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10844

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      Exploring the overproduction of amino acids using the bilevel optimization framework OptKnock (pages 887–899)

      Priti Pharkya, Anthony P. Burgard and Costas D. Maranas

      Article first published online: 30 DEC 2003 | DOI: 10.1002/bit.10857

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