Short Papers for The Moynihan Prize and Medal
The effects of carotid endarterectomy on the mechanical properties of the carotid sinus and carotid sinus nerve activity in atherosclerotic patients
Article first published online: 7 DEC 2005
Copyright © 1974 British Journal of Surgery Society Ltd.
British Journal of Surgery
Volume 61, Issue 10, pages 805–810, October 1974
How to Cite
Angell-James, J. E. and Lumley, J. S. P. (1974), The effects of carotid endarterectomy on the mechanical properties of the carotid sinus and carotid sinus nerve activity in atherosclerotic patients. Br J Surg, 61: 805–810. doi: 10.1002/bjs.1800611014
- Issue published online: 7 DEC 2005
- Article first published online: 7 DEC 2005
The hypothesis that instability of blood pressure occurring after carotid endarterectomy is related to interference with mechanical properties of the arterial wall in the region of the carotid sinus was investigated in 11 patients undergoing carotid surgery for transient ischaemic neurological disturbances. The operative procedure was found to change the mechanical properties of the arterial wall, there being an overall increase in diameter and reduction in distensibility, and these changes were reflected in the recorded change of spontaneous sinus nerve activity and the systemic blood pressure. It is suggested that the sinus nerve and carotid baroreceptor region should be carefully preserved during carotid endarterectomy to prevent reflex postoperative hypertension. Should hypotension occur in the postoperative phase it can be treated by local anaesthesia of the sinus region, anaesthetic blockade being maintained until secondary adaptation of the receptors takes place.