Role of fine-needle aspiration cytology and needle-core biopsy in the diagnosis of lobular carcinoma of the breast
Article first published online: 6 DEC 2005
Copyright © 1994 British Journal of Surgery Society Ltd.
British Journal of Surgery
Volume 81, Issue 9, pages 1315–1317, September 1994
How to Cite
Sadler, G. P., McGee, S., Dallimore, N. S., Monypenny, I. J., Douglas-Jones, A. G., Lyons, K. and Horgan, K. (1994), Role of fine-needle aspiration cytology and needle-core biopsy in the diagnosis of lobular carcinoma of the breast. Br J Surg, 81: 1315–1317. doi: 10.1002/bjs.1800810918
- Issue published online: 6 DEC 2005
- Article first published online: 6 DEC 2005
- Manuscript Accepted: 14 FEB 1994
Fine-needle aspiration cytology (FNAC) plays a key role in the preoperative diagnosis of carcinoma of the breast but is less reliable in the diagnosis of infiltrating lobular carcinoma. The method of diagnosis was reviewed in 56 patients with lobular carcinoma who had attended screening and symptomatic clinics. In 29 patients FNAC results demonstrated malignant cells; 15 of these had palpable disease and the mean tumour size was 21 mm. In 27 patients FNAC failed to demonstrate malignant cells; 13 lesions were palpable and the mean tumour size was 23 mm. Ten patients were diagnosed by needle-core biopsy when FNAC was not diagnostic. FNAC may fail to diagnose even large lobular carcinoma and needle-core biopsy is strongly recommended in this situation.