Long-term outcome after surgery for asymptomatic small hepatocellular carcinoma
Article first published online: 7 DEC 2005
Copyright © 1996 British Journal of Surgery Society Ltd.
British Journal of Surgery
Volume 83, Issue 3, pages 330–333, March 1996
How to Cite
Lee, C.-S., Sheu, J.-C., Wang, M. and Hsu, H.-C. (1996), Long-term outcome after surgery for asymptomatic small hepatocellular carcinoma. Br J Surg, 83: 330–333. doi: 10.1002/bjs.1800830310
- Issue published online: 7 DEC 2005
- Article first published online: 7 DEC 2005
- Manuscript Accepted: 13 FEB 1995
The subjects of this study were 48 asymptomatic patients who had surgery for small hepatocellar carcinoma (HCC). There were 42 men and six women with mean(s.d.) tumour size of 3·31(1·46) cm and age 55·0(7·4) years. Follow-up was for a minimum of 10 years. The main concern of this study was a univariate analysis of factors that might affect long-term survival after surgery, which was 50 per cent at 5 years and 31 per cent at 10 years. A high incidence of recurrent HCC (37 of 48 patients) was observed but reoperation further prolonged life in some cases. The significant prognostic factors detected by multivariate analysis were: histological classification, functional liver reserve and histology of the resection margin. Tumour size, gross appearance of tumour, presence of liver cirrhosis, serum α-fetoprotein level, age or sex did not affect the prognosis.