Peritoneal defences and peritoneum-associated lymphoid tissue
Article first published online: 6 DEC 2005
Copyright © 1996 British Journal of Surgery Society Ltd.
British Journal of Surgery
Volume 83, Issue 8, pages 1031–1036, August 1996
How to Cite
Heel, K. A. and Hall, J. C. (1996), Peritoneal defences and peritoneum-associated lymphoid tissue. Br J Surg, 83: 1031–1036. doi: 10.1002/bjs.1800830804
- Issue published online: 6 DEC 2005
- Article first published online: 6 DEC 2005
- Manuscript Accepted: 22 FEB 1996
The peritoneum is mainly protected by the innate immune system. This consists of mechanical clearance of the peritoneal cavity, activation of complement, and the actions of polymorphonuclear neutrophils and macrophages. The specific immune system, which is mediated by the activity of lymphocytes, provides a secondary amplification system that may be of great importance for patients with intraperitoneal sepsis. This review provides an overview of the relevant innate immune mechanisms and explores the possible role of peritoneum-associated lymphoid tissue.