Surgical management of primary and recurrent retroperitoneal liposarcoma
Version of Record online: 25 OCT 2004
Copyright © 2004 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
British Journal of Surgery
Volume 92, Issue 2, pages 246–252, February 2005
How to Cite
Neuhaus, S. J., Barry, P., Clark, M. A., Hayes, A. J., Fisher, C. and Thomas, J. M. (2005), Surgical management of primary and recurrent retroperitoneal liposarcoma. Br J Surg, 92: 246–252. doi: 10.1002/bjs.4802
- Issue online: 31 JAN 2005
- Version of Record online: 25 OCT 2004
- Manuscript Accepted: 30 JUN 2004
- Lumley Exchange Fellowship of the Royal Australasian College of Surgeons
Surgery plays a dominant role in the initial and subsequent treatment of retroperitoneal liposarcoma (RPLS). This study was a review of outcomes of patients treated at the Royal Marsden Hospital.
Records of all patients who had surgery for RPLS since 1990 were reviewed, with particular attention to local recurrence and disease-specific survival. Patients with primary RPLS and those with recurrent RPLS, who had palliative surgery after a variable number of operations performed elsewhere, were considered separately.
Seventy-two patients had surgery for primary RPLS, over half of whom underwent resection of a contiguous organ to achieve clearance. Follow-up of at least 12 months was available for 58 patients. Thirty-four patients had no evidence of recurrence after median follow-up of 26 (range 12–151) months. Low-grade tumour and macroscopic clearance of tumour were significantly associated with a reduced risk of local recurrence and improved survival. Forty-seven patients had palliative surgery for recurrent RPLS. Median survival from time of last operation to death was 27 (range 0–79) months. Follow-up was to a median of 68 (range 14–261) months.
Patients with low-grade RPLS that has been completely resected at the initial operation have the most favourable prognosis. Palliative resection is worthwhile to treat troublesome symptoms of recurrence Copyright © 2004 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.